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AB23701

Anti-DPL 抗体

Anti-DPL antibody

1

(2 Reviews)

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(0 Publication)

Rabbit Polyclonal DPL antibody. Suitable for WB and reacts with Mouse samples. Immunogen corresponding to Synthetic Peptide within Human PRND aa 100-150.

別名を表示する

DPL, UNQ1830/PRO3443, PRND, Prion-like protein doppel, PrPLP, Prion protein 2

1 Images
Western blot - Anti-DPL antibody (AB23701)
  • WB

Unknown

Western blot - Anti-DPL antibody (AB23701)

All lanes:

Western blot - Anti-DPL antibody (ab23701) at 2 µg/mL

Lane 1:

27ug mouse spleen 100k x g supernatant.

Lane 2:

54ug mouse spleen 100k x g supernatant.

Predicted band size: 20 kDa

Observed band size: 19 kDa,25 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse

アプリケーション

WB

applications

免疫原

Synthetic Peptide within Human PRND aa 100-150. The exact immunogen used to generate this antibody is proprietary information.

Q9UKY0

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "2 µg/mL", "WB-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
バッファー組成
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 50% Glycerol (glycerin, glycerine), 0.1% BSA
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The term DPL often refers to a protein involved in cellular processes and may also be known as "dpl" or "aa dpl". Its exact molecular mass can vary based on the isoform and the species in which it is found. DPL is expressed in various tissues including the brain liver and heart making it an important target for therapeutic studies in diverse physiological contexts. Researchers investigate this protein to understand better its mechanical roles in maintaining cellular functions.
Biological function summary

DPL participates in cellular signaling and structural integrity. It sometimes acts as part of a larger protein complex facilitating communication and interactions between cells. The molecular interactions with other proteins help maintain cellular homeostasis. The coupling with other cellular components might also contribute to energy metabolism and cytoskeletal organization critical to cell health and function.

Pathways

DPL plays a role in specific signaling pathways like the MAPK/ERK and PI3K/AKT pathways. These pathways are significant for cell proliferation differentiation and survival. DPL interacts with other proteins such as Raf and PI3K enabling these signaling cascades essential for cellular responses to external stimuli. The pathways involving DPL are important for understanding various cellular mechanisms and how they relate to broader biological activities across systems.

DPL has connections to certain conditions including cancer and cardiovascular diseases. Abnormal expression or mutations in DPL can disrupt normal cellular signaling contributing to tumorigenesis and heart dysfunction. In cancer DPL may interact with oncogenes like KRAS affecting tumor growth and spread. In heart disorders alterations in DPL-associated pathways could impact cardiac cell function connecting it to other proteins such as troponin related to heart muscle contraction abnormalities.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Required for normal acrosome reaction and for normal male fertility (By similarity). Can bind Cu(2+) (PubMed : 15218028, PubMed : 20411530).
See full target information PRND
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