AB126080

Anti-Dkk3 抗体

Anti-Dkk3 antibody

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(5 Publications)

Rabbit Polyclonal Dkk3 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human DKK3 aa 50 to C-terminus.

別名を表示する

REIC, UNQ258/PRO295, DKK3, Dickkopf-related protein 3, Dickkopf-3, Dkk-3, hDkk-3

1 Images

Unknown

Western blot - Anti-Dkk3 antibody (AB126080)

Gel concentration : 10%

All lanes:

Western blot - Anti-Dkk3 antibody (ab126080) at 1/1000 dilution

All lanes:

293T whole cell lysate at 30 µg

Predicted band size: 38 kDa

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Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Human

アプリケーション

applications

免疫原

Recombinant Fragment Protein within Human DKK3 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9UBP4

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Immunogen

バッファー組成

pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA

出荷温度

Blue Ice

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

See full target information DKK3

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文献 (5)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in oncology 12:948023 PubMed35924156

2022

Apogossypolone Inhibits Cell Proliferation and Epithelial-Mesenchymal Transition in Cervical Cancer Activating DKK3.

Applications

Unspecified application

Species

Unspecified reactive species

Yuling Li,Jinfeng Qu,Lu Liu,Yu Sun,Junhua Zhang,Sai Han,Youzhong Zhang

European journal of medical research 26:93 PubMed34391478

2021

Dickkopf-related protein 3 alters aerobic glycolysis in pancreatic cancer BxPC-3 cells, promoting CD4 T-cell activation and function.

Applications

Unspecified application

Species

Unspecified reactive species

Qingqu Guo,Yiming Chu,Hongbo Li,Dike Shi,Lele Lin,Weifeng Lan,Dan Wu

Cells 10: PubMed33670899

2021

Integrated Proteomic and Phosphoproteomics Analysis of DKK3 Signaling Reveals Activated Kinase in the Most Aggressive Gallbladder Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Kirti Gondkar,Gajanan Sathe,Neha Joshi,Bipin Nair,Akhilesh Pandey,Prashant Kumar

Frontiers in oncology 9:1121 PubMed31737564

2019

Dickkopf Homolog 3 Acts as a Potential Tumor Suppressor in Gallbladder Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Kirti Gondkar,Krishna Patel,Geeta V Patil Okaly,Bipin Nair,Akhilesh Pandey,Harsha Gowda,Prashant Kumar

Oncogene 34:1520-31 PubMed24727892

2014

CD58, a novel surface marker, promotes self-renewal of tumor-initiating cells in colorectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

S Xu,Z Wen,Q Jiang,L Zhu,S Feng,Y Zhao,J Wu,Q Dong,J Mao,Y Zhu

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Dkk3 抗体

Anti-Dkk3 antibody

Western blot - Anti-Dkk3 antibody (AB126080)

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

長期保存温度

分注に関する情報

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (5)

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組合せ製品

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Secondary Antibodies

Primary Antibodies

Primary Antibodies

Abcam product promise