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AB317384

Anti-DHRS1 抗体 [S01-9E4]

Anti-DHRS1 antibody [S01-9E4]

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Rabbit Monoclonal Dhrs1 antibody. Suitable for WB and reacts with Rat samples. Immunogen corresponding to Recombinant Fragment Protein within Human DHRS1.
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Western blot - Anti-DHRS1 Antibody [S01-9E4] (AB317384)
  • WB

Supplier Data

Western blot - Anti-DHRS1 Antibody [S01-9E4] (AB317384)

All lanes:

Western blot - Anti-DHRS1 Antibody [S01-9E4] (ab317384) at 1/1000 dilution

All lanes:

C6 cell lysate

Predicted band size: 34 kDa

false

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

S01-9E4

アイソタイプ

IgG

キャリアフリー

No

交差種

Rat

アプリケーション

WB

applications

免疫原

Recombinant Fragment Protein within Human DHRS1.

Q96LJ7

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification
バッファー組成
pH: 7.4 Preservative: 0.01% Sodium azide Constituents: 55.08% Water, 40% Glycerol (glycerin, glycerine), 0.98% Tris glycine, 0.88% Sodium chloride, 0.05% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

DHRS1 also known as dehydrogenase/reductase SDR family member 1 is an enzyme involved in biochemical reactions. It belongs to the short-chain dehydrogenase/reductase (SDR) family and has a mass of about 33 kDa. This enzyme participates in redox reactions specifically by catalyzing the oxidation and reduction processes involving small substrates. DHRS1 is mainly expressed in liver and kidney tissues which suggests its role in metabolic processes associated with these organs.
Biological function summary

DHRS1 plays an important role in lipid metabolism. It helps in the conversion of steroid precursors and participates in the inactivation of steroid hormones. This enzyme does not form part of a complex but interacts with other enzymes within the same family to maintain balanced metabolic functions. Its activity assists in ensuring proper physiological levels of various metabolites and hormones.

Pathways

DHRS1 integrates into the lipid metabolism and steroid hormone biosynthesis pathways. It interacts with key proteins involved in oxidative metabolism such as 11β-hydroxysteroid dehydrogenase contributing to the regulation and conversion processes within these pathways. These interactions are important in controlling the balance of metabolites and support the physiological functionality of lipids and hormones.

DHRS1 is associated with metabolic syndrome and non-alcoholic fatty liver disease (NAFLD). Changes in DHRS1 activity can affect lipid processing and hormone regulation leading to these metabolic conditions. It may connect to proteins like peroxisome proliferator-activated receptor gamma (PPARγ) which also influences lipid metabolism and has a role in the onset of metabolic diseases. Understanding DHRS1's interactions and alterations could provide insight into therapeutic targets for these conditions.

製品プロトコール

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ターゲットの情報

See full target information Dhrs1

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