Anti-DcR3 抗体 (ab8405)
Key features and details
- Rabbit polyclonal to DcR3
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-DcR3 antibody
DcR3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to DcR3 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human DcR3 aa 31-46. Peptide corresponding to amino acids 31 to 46 of human DcR3 precursor (1,2).
(Peptide available asab8437) -
ポジティブ・コントロール
- WB: Human heart, brain, and kidney tissue lysates. IHC-P: Human heart tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Ion Exchange Chromatography -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
軽鎖の種類
unknown -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab8405の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use a concentration of 1 µg/ml.
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WB |
Use a concentration of 0.5 µg/ml. Detects a band of approximately 33 kDa.
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特記事項 |
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IHC-P
Use a concentration of 1 µg/ml. |
WB
Use a concentration of 0.5 µg/ml. Detects a band of approximately 33 kDa. |
ターゲット情報
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機能
Decoy receptor for the cytotoxic ligands TNFS14/LIGHT and TNFSF6/FASL. Protects against apoptosis. -
組織特異性
Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells. -
配列類似性
Contains 4 TNFR-Cys repeats. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 8771 Human
- Omim: 603361 Human
- SwissProt: O95407 Human
- Unigene: 434878 Human
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別名
- DcR3 antibody
- Decoy receptor 3 antibody
- Decoy receptor for Fas ligand antibody
see all
画像
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All lanes : Anti-DcR3 antibody (ab8405) at 1/500 dilution
Lane 1 : Human heart tissue lysate
Lane 2 : Human brain tissue lysate
Lane 3 : Human kidney tissue lysate
Observed band size: 33 kDa why is the actual band size different from the predicted? -
ab8405 at 1µg/ml staining DcR3 in human heart tissue by IHC.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab8405 は 2 報の論文で使用されています。
- Chen X et al. Decoy receptor-3 regulates inflammation and apoptosis via PI3K/AKT signaling pathway in coronary heart disease. Exp Ther Med 17:2614-2622 (2019). PubMed: 30906453
- Yu W et al. DcR3 regulates the growth and metastatic potential of SW480 colon cancer cells. Oncol Rep 30:2741-8 (2013). PubMed: 24101127