Anti-Dab1 (phospho Y232) 抗体 (ab78200)
Key features and details
- Rabbit polyclonal to Dab1 (phospho Y232)
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Dab1 (phospho Y232) antibody
Dab1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Dab1 (phospho Y232) -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Synthetic peptide corresponding to Human Dab1 (phospho Y232).
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ポジティブ･コントロール
- Extracts from LOVO cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab78200の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).
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| 特記事項 |
|---|
|
WB
1/500 - 1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa). |
ターゲット情報
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機能
Adapter molecule functioning in neural development. May regulate SIAH1 activity. -
配列類似性
Contains 1 PID domain. -
ドメイン
The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins. -
翻訳後修飾
Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling. - Information by UniProt
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参照データベース
- Entrez Gene: 1600 Human
- Entrez Gene: 13131 Mouse
- Entrez Gene: 266729 Rat
- Omim: 603448 Human
- SwissProt: O75553 Human
- SwissProt: P97318 Mouse
- SwissProt: Q8CJH2 Rat
- Unigene: 477370 Human
see all -
別名
- Dab 1 antibody
- Dab reelin signal transducer 1 antibody
- Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
see all
画像
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Western blot - Anti-Dab1 (phospho Y232) antibody (ab78200)All lanes : Anti-Dab1 (phospho Y232) antibody (ab78200) at 1/500 dilution
Lane 1 : Extracts from LOVO cells
Lane 2 : Extracts from LOVO cells plus 5µg immunizing peptide
Lysates/proteins at 5 µg per lane.
Predicted band size: 67 kDa
Observed band size: 67 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab78200 は 2 報の論文で使用されています。
- Racetin A et al. Expression and localization of DAB1 and Reelin during normal human kidney development. Croat Med J 60:521-531 (2019). PubMed: 31894918
- Rogers JT et al. Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density. Learn Mem 18:558-64 (2011). PubMed: 21852430