Anti-Cytomegalovirus pp65 抗体 [CH12] (ab53489)
Key features and details
- Mouse monoclonal [CH12] to Cytomegalovirus pp65
- Suitable for: ICC/IF, WB
- Reacts with: Human cytomegalovirus
- Isotype: IgG
製品の概要
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製品名
Anti-Cytomegalovirus pp65 antibody [CH12]
Cytomegalovirus pp65 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [CH12] to Cytomegalovirus pp65 -
由来種
Mouse -
特異性
ab53489 is reactive with pp65 (UL83) of Cytomegalovirus. -
アプリケーション
適用あり: ICC/IF, WBmore details -
種交差性
交差種: Human cytomegalovirus -
免疫原
Tissue, cells or virus corresponding to Cytomegalovirus pp65. HCMV AD169 IC Extract
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
CH12 -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab53489の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF |
Use a concentration of 10 µg/ml.
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| WB |
Use a concentration of 10 µg/ml.
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| 特記事項 |
|---|
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ICC/IF
Use a concentration of 10 µg/ml. |
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WB
Use a concentration of 10 µg/ml. |
ターゲット情報
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関連性
Cytomegalovirus is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella zoster virus (which causes chicken pox), and Epstein Barr virus (which causes infectious mononucleosis). These viruses share a characteristic ability to remain dormant within the body over a long period. CMV viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. pp65 is a 65kD phosphorylated glycoprotein and is the most abundant of the late antigens. -
参照データベース
- Entrez Gene: 1487754 Human cytomegalovirus
- SwissProt: P06725 Human cytomegalovirus
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別名
- 65 kDa matrix phosphoprotein antibody
- 65 kDa phosphoprotein antibody
- Tegument protein pp65 antibody
- Tegument protein UL83 antibody
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (8)
ab53489 は 8 報の論文で使用されています。
- Zhao M et al. Bilobalide Enhances AMPK Activity to Improve Liver Injury and Metabolic Disorders in STZ-Induced Diabetes in Immature Rats via Regulating HMGB1/TLR4/NF-?B Signaling Pathway. Biomed Res Int 2021:8835408 (2021). PubMed: 33959665
- Feng FE et al. HCMV modulates c-Mpl/IEX-1 pathway-mediated megakaryo/thrombopoiesis via PDGFRα and αvβ3 receptors after allo-HSCT. J Cell Physiol 236:6726-6741 (2021). PubMed: 33611789
- Gao H et al. MicroRNA-93 contributes to the suppression of lung inflammatory responses in LPS-induced acute lung injury in mice via the TLR4/MyD88/NF-?B signaling pathway. Int J Mol Med 46:561-570 (2020). PubMed: 32468034
- Zhang HS et al. Gastrodin combined with rhynchophylline inhibits cerebral ischaemia-induced inflammasome activation via upregulating miR-21-5p and miR-331-5p. Life Sci 239:116935 (2019). PubMed: 31610203
- Kiener R et al. Vaccine vectors based on Adenovirus 19a/64 exhibit broad cellular tropism and potently restimulate HCMV-specific T cell responses ex vivo. Sci Rep 8:1474 (2018). PubMed: 29367743
- Kiener R et al. Efficient Delivery of Human Cytomegalovirus T Cell Antigens by Attenuated Sendai Virus Vectors. J Virol 92:N/A (2018). PubMed: 29769344
- Wu Z et al. Relationship between T-cell receptor beta chain sequences and human cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients. Mol Med Rep 15:3898-3904 (2017). PubMed: 28440401
- Walker JD et al. Cytomegalovirus-infected human endothelial cells can stimulate allogeneic CD4+ memory T cells by releasing antigenic exosomes. J Immunol 182:1548-59 (2009). WB . PubMed: 19155503
