Anti-Cytomegalovirus pp65 抗体 [1-L-11] (ab31624)
Key features and details
- Mouse monoclonal [1-L-11] to Cytomegalovirus pp65
- Suitable for: WB, ELISA, ICC/IF
- Reacts with: Human cytomegalovirus
- Isotype: IgG1
製品の概要
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製品名
Anti-Cytomegalovirus pp65 antibody [1-L-11]
Cytomegalovirus pp65 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [1-L-11] to Cytomegalovirus pp65 -
由来種
Mouse -
特異性
Recognizes human pp65 immediate early nuclear antigen. The clone number has been updated from (8.V.035) to (1-L-11) both clone numbers name the same antibody clone. -
アプリケーション
適用あり: WB, ELISA, ICC/IFmore details -
種交差性
交差種: Human cytomegalovirus -
免疫原
Tissue, cells or virus corresponding to Human Cytomegalovirus pp65.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: PBS, 40% Glycerol -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
1-L-11 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab31624の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500.
|
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| ELISA |
1/5000.
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| ICC/IF |
Use at an assay dependent dilution.
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| 特記事項 |
|---|
|
WB
1/500. |
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ELISA
1/5000. |
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ICC/IF
Use at an assay dependent dilution. |
ターゲット情報
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関連性
Cytomegalovirus is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella zoster virus (which causes chicken pox), and Epstein Barr virus (which causes infectious mononucleosis). These viruses share a characteristic ability to remain dormant within the body over a long period. CMV viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. pp65 is a 65kD phosphorylated glycoprotein and is the most abundant of the late antigens. -
参照データベース
- Entrez Gene: 1487754 Human cytomegalovirus
- SwissProt: P06725 Human cytomegalovirus
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別名
- 65 kDa matrix phosphoprotein antibody
- 65 kDa phosphoprotein antibody
- Tegument protein pp65 antibody
- Tegument protein UL83 antibody
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (8)
ab31624 は 8 報の論文で使用されています。
- Zhu X et al. Kaempferitrin alleviates LPS-induced septic acute lung injury in mice through downregulating NF-κB pathway. Allergol Immunopathol (Madr) 51:1-7 (2023). PubMed: 37937489
- He XY et al. Compound-42 alleviates acute kidney injury by targeting RIPK3-mediated necroptosis. Br J Pharmacol 180:2641-2660 (2023). PubMed: 37248964
- Yan K et al. Leonurine inhibits the TXNIP/NLRP3 and NF-κB pathways via Nrf2 activation to alleviate carrageenan-induced pleurisy in mice. Phytother Res 36:2161-2172 (2022). PubMed: 35285100
- Zhao XQ et al. The circular RNA circ_0099630/miR-940/receptor-associated factor 6 regulation cascade modulates the pathogenesis of periodontitis. J Dent Sci 17:1566-1576 (2022). PubMed: 36299308
- Lu H et al. TNF-α induces AQP4 overexpression in astrocytes through the NF-κB pathway causing cellular edema and apoptosis. Biosci Rep 42:N/A (2022). PubMed: 35260880
- Ma YS et al. MicroRNA-499 serves as a sensitizer for lung cancer cells to radiotherapy by inhibition of CK2a-mediated phosphorylation of p65. Mol Ther Oncolytics 21:171-182 (2021). PubMed: 33997273
- Wang Y et al. YAP1 promotes high glucose-induced inflammation and extracellular matrix deposition in glomerular mesangial cells by modulating NF-κB/JMJD3 pathway. Exp Ther Med 22:1349 (2021). PubMed: 34659495
- Shimizu D et al. Infection of endotheliotropic human cytomegalovirus of trabecular meshwork cells. Jpn J Ophthalmol 62:667-676 (2018). PubMed: 30191418