Anti-Cyp26B1 抗体 (ab113236)
Key features and details
- Rabbit polyclonal to Cyp26B1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Cyp26B1 antibody
Cyp26B1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Cyp26B1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Recombinant full length protein corresponding to Human Cyp26B1.
Database link: P450 26B -
ポジティブ・コントロール
- Human Adrenal gland and Human brain, cerebellum tissues; HepG2 whole cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 79.99% Tris glycine -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab113236の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 58 kDa.
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IHC-P |
Use a concentration of 10 µg/ml.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 58 kDa. |
IHC-P
Use a concentration of 10 µg/ml. |
ターゲット情報
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機能
Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Involved in the specific inactivation of all-trans-retinoic acid (all-trans-RA), with a preference for the following substrates: all-trans-RA > 9-cis-RA > 13-cis-RA. Generates several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA, and 18-OH-RA. Esential for postnatal survival. Plays a central role in germ cell development: acts by degrading RA in the developing testis, preventing STRA8 expression, thereby leading to delay of meiosis. Required for the maintenance of the undifferentiated state of male germ cells during embryonic development in Sertoli cells, inducing arrest in G0 phase of the cell cycle and preventing meiotic entry. Plays a role in skeletal development, both at the level of patterning and in the ossification of bone and the establishment of some synovial joints. -
組織特異性
Highly expressed in brain, particularly in the cerebellum and pons. -
関連疾患
Radiohumeral fusions with other skeletal and craniofacial anomalies -
配列類似性
Belongs to the cytochrome P450 family. -
細胞内局在
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 56603 Human
- Entrez Gene: 232174 Mouse
- Entrez Gene: 312495 Rat
- Omim: 605207 Human
- SwissProt: Q9NR63 Human
- SwissProt: Q811W2 Mouse
- SwissProt: G3V7X8 Rat
- Unigene: 91546 Human
see all -
別名
- CP26 antibody
- CP26B_HUMAN antibody
- CYP26A2 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cyp26B1 antibody (ab113236)
ab113236, at 10µg/ml, staining Cyp26B1 in Formalin-fixed, Paraffin-embedded Human Adrenal tissue by Immunohistochemistry.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cyp26B1 antibody (ab113236)
ab113236, at 10µg/ml, staining Cyp26B1 in Formalin-fixed, Paraffin-embedded Human Brain cerebellum tissue by Immunohistochemistry.
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Anti-Cyp26B1 antibody (ab113236) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg
Predicted band size: 58 kDa
7.5% SDS PAGE.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab113236 は 1 報の論文で使用されています。
- Mao S et al. A Schwann cell-enriched circular RNA circ-Ankib1 regulates Schwann cell proliferation following peripheral nerve injury. FASEB J 33:12409-12424 (2019). PubMed: 31415184