Anti-CSRP1 抗体 (ab70010)
Key features and details
- Rabbit polyclonal to CSRP1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CSRP1 antibody
CSRP1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CSRP1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Rat
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免疫原
Synthetic peptide (Human) from an internal region
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ポジティブ･コントロール
- IHC-P: Human brain tissue. WB: HeLa, HepG2, COLO, Jurkat cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab70010の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).
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| IHC-P |
1/50 - 1/100.
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| 特記事項 |
|---|
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WB
1/500 - 1/1000. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa). |
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IHC-P
1/50 - 1/100. |
ターゲット情報
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機能
Could play a role in neuronal development. -
配列類似性
Contains 2 LIM zinc-binding domains. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 1465 Human
- Entrez Gene: 29276 Rat
- Omim: 123876 Human
- SwissProt: P21291 Human
- SwissProt: P47875 Rat
- Unigene: 108080 Human
- Unigene: 108075 Rat
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別名
- CRP 1 antibody
- CRP antibody
- CRP1 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CSRP1 antibody (ab70010)immunohistochemical analysis of paraffin embedded human brain tissue using ab70010 at 1/50 dilution. Right panel was treated with immunising peptide.
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Western blot - Anti-CSRP1 antibody (ab70010)All lanes : Anti-CSRP1 antibody (ab70010) at 1/500 dilution
Lane 1 : HeLa cell extract
Lane 2 : HepG2 cell extract
Lane 3 : COLO cell extract
Lane 4 : Jurkat cell extract
Lane 5 : HeLa cell extract with immunising peptide at 10 µg
Lysates/proteins at 30 µg per lane.
Predicted band size: 21 kDa
Observed band size: 21 kDa
Additional bands at: 33 kDa, 50 kDa, 80 kDa. We are unsure as to the identity of these extra bands.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab70010 は 5 報の論文で使用されています。
- Yuan FY et al. Tanshinone IIA improves diabetes mellitus via the NF-?B-induced AMPK signal pathway. Exp Ther Med 16:4225-4231 (2018). PubMed: 30344697
- Kamar A et al. A Novel Role forCSRP1in a Lebanese Family with Congenital Cardiac Defects. Front Genet 8:217 (2017). PubMed: 29326753
- Heidersbach A et al. microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart. Elife 2:e01323 (2013). WB ; Mouse . PubMed: 24252873
- Järvinen PM et al. Cysteine-rich protein 1 is regulated by transforming growth factor-ß1 and expressed in lung fibrosis. J Cell Physiol 227:2605-12 (2012). WB ; Human . PubMed: 21882188
- Meves A et al. Beta1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation. Proc Natl Acad Sci U S A 108:15213-8 (2011). WB, ICC/IF ; Mouse . PubMed: 21876123