Anti-Corneodesmosin/S protein 抗体 (ab118835)
Key features and details
- Rabbit polyclonal to Corneodesmosin/S protein
- Suitable for: IHC-Fr, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Corneodesmosin/S protein antibody
Corneodesmosin/S protein 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Corneodesmosin/S protein -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Fr, WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human Corneodesmosin/S protein (N terminal).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.02% Sodium azide -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab118835の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-Fr |
Use at an assay dependent concentration.
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| WB |
Use at an assay dependent concentration.
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| 特記事項 |
|---|
|
IHC-Fr
Use at an assay dependent concentration. |
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WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Important for the epidermal barrier integrity. -
組織特異性
Exclusively expressed in skin. -
関連疾患
Defects in CDSN are a cause of hypotrichosis simplex of the scalp (HTSS) [MIM:146520]; also known as hypotrichosis Spanish type. HTSS is an autosomal dominant form of isolated alopecia. Affected individuals have normal hair in early childhood but experience progressive loss of scalp hair beginning in the middle of the first decade and almost complete baldness by the third decade.
Defects in CDSN are the cause of peeling skin syndrome type B (BPSS) [MIM:270300]; also known as peeling skin syndrome or deciduous skin or keratolysis exfoliativa congenita. BPSS is a genodermatosis characterized by the continuous shedding of the outer layers of the epidermis, associated with pruritus and atopy. It is an ichthyosiform erythroderma characterized by lifelong patchy peeling of the entire skin with onset at birth or shortly thereafter. Several patients have been reported with high IgE levels. -
細胞内局在
Secreted. Found in corneodesmosomes, the intercellular structures that are involved in desquamation. - Information by UniProt
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参照データベース
- Entrez Gene: 1041 Human
- Omim: 602593 Human
- SwissProt: Q15517 Human
- Unigene: 556031 Human
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別名
- AI747712 antibody
- CDSN antibody
- CDSN_HUMAN antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab118835 は論文での使用が確認できていません。