Anti-Complex I subunit 8 kDa 抗体 [17C8E4E11] (ab110245)
![Western blot - Anti-Complex I subunit 8 kDa antibody [17C8E4E11] (ab110245)](https://www.abcam.co.jp/ps/products/110/ab110245/Images/ab110245-123425-anti-complex-i-subunit-8-kda-antibody-17c8e4e11-western-blot.jpg "Western blot - Anti-Complex I subunit 8 kDa antibody [17C8E4E11] (ab110245)")
Key features and details
- Mouse monoclonal [17C8E4E11] to Complex I subunit 8 kDa
- Suitable for: WB
- Reacts with: Mouse, Rat, Cow, Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Complex I subunit 8 kDa antibody [17C8E4E11] -
製品の詳細
Mouse monoclonal [17C8E4E11] to Complex I subunit 8 kDa -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Rat, Cow, Human -
免疫原
Full length native protein (purified). This information is considered to be commercially sensitive.
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ポジティブ･コントロール
- Isolated mitochondria from Human, Bovine, Rat and Mouse hearts.
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特記事項
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Product was previously marketed under the MitoSciences sub-brand.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Do Not Freeze. -
バッファー
pH: 7.5
Preservative: 0.02% Sodium azide
Constituent: HEPES buffered saline -
Concentration information loading... -
特記事項（精製）
ab110245 was produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation. -
ポリ/モノ
モノクローナル -
クローン名
17C8E4E11 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab110245の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml.
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| 特記事項 |
|---|
|
WB
Use a concentration of 1 µg/ml. |
ターゲット情報
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関連性
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. -
細胞内局在
Mitochondrial -
参照データベース
- Entrez Gene: 287027 Cow
- Entrez Gene: 4728 Human
- Entrez Gene: 225887 Mouse
- Entrez Gene: 293652 Rat
- Omim: 602141 Human
- SwissProt: O00217 Human
- SwissProt: Q8K3J1 Mouse
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別名
- BC021616 antibody
- CI 23k antibody
- CI23KD antibody
see all
画像
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Western blot - Anti-Complex I subunit 8 kDa antibody [17C8E4E11] (ab110245)All lanes : Anti-Complex I subunit 8 kDa antibody [17C8E4E11] (ab110245) at 1 µg/ml
Lane 1 : Human heart mitochondria at 10 µg
Lane 2 : Bovine heart mitochondria at 4 µg
Lane 3 : Rat heart mitochondria at 10 µg
Lane 4 : Mouse heart mitochondria at 10 µg
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (15)
ab110245 は 15 報の論文で使用されています。
- Costa TJ et al. Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage. Vascul Pharmacol 142:106946 (2022). PubMed: 34838735
- Gundu C et al. GSK2606414 attenuates PERK/p-eIF2α/ATF4/CHOP axis and augments mitochondrial function to mitigate high glucose induced neurotoxicity in N2A cells. Curr Res Pharmacol Drug Discov 3:100087 (2022). PubMed: 35146419
- Wu P et al. Ginsenoside Rg3 alleviates septic liver injury by regulating the lncRNA TUG1/miR-200c-3p/SIRT1 axis. J Inflamm (Lond) 18:31 (2021). PubMed: 34930287
- Li S et al. The UL16 protein of HSV-1 promotes the metabolism of cell mitochondria by binding to ANT2 protein. Sci Rep 11:14001 (2021). PubMed: 34234233
- Martínez J et al. Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells. Biochem J 476:2463-2486 (2019). PubMed: 31431479