Anti-CLEC5A 抗体 (ab184156)
Key features and details
- Rabbit polyclonal to CLEC5A
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CLEC5A antibody
CLEC5A 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CLEC5A -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment within Human CLEC5A aa 1-188. The exact sequence is proprietary.
Database link: Q9NY25 -
ポジティブ･コントロール
- K562 whole cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab184156の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 22 kDa.
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| 特記事項 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 22 kDa. |
ターゲット情報
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機能
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation (By similarity). Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release. -
組織特異性
Expressed in peripheral blood monocytes and in the monocyte/macrophage cell lines U-937 and Mono-Mac-6, but not in cell lines of other origins. Expression is down-regulated when monocytes differentiate into dendritic cells. -
配列類似性
Contains 1 C-type lectin domain. -
翻訳後修飾
N-glycosylated. Contains sialic acid residues. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 23601 Human
- Omim: 604987 Human
- SwissProt: Q9NY25 Human
- Unigene: 446235 Human
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別名
- C type lectin domain family 5 member A antibody
- C-type lectin domain family 5 member A antibody
- C-type lectin superfamily member 5 antibody
see all
画像
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Western blot - Anti-CLEC5A antibody (ab184156)Anti-CLEC5A antibody (ab184156) at 1/1000 dilution + K562 whole cell lysate at 30 µg
Predicted band size: 22 kDa12% SDS PAGE
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab184156 は論文での使用が確認できていません。