AB239078

Anti-CLEC4C 抗体 [EPR21985]

Name: Anti-CLEC4C 抗体 [EPR21985] (ab239078) | Abcam
Brand: Abcam Limited
SKU: AB239078
Price: 36000 JPY
Availability: InStock
Rating: 5 (1 reviews)

Anti-CLEC4C antibody [EPR21985]

20ul selling size
RabMAb
Recombinant
詳細を見る

(1 Review)

(4 Publications)

Rabbit Recombinant Monoclonal CLEC4C antibody. Suitable for Flow Cyt, IHC-P and reacts with Human samples. Cited in 4 publications.

別名を表示する

CD303, BDCA2, CLECSF11, CLECSF7, DLEC, HECL, UNQ9361/PRO34150, CLEC4C, C-type lectin domain family 4 member C, Blood dendritic cell antigen 2, C-type lectin superfamily member 7, Dendritic lectin, BDCA-2

3 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC4C antibody [EPR21985] (AB239078)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC4C antibody [EPR21985] (AB239078)

Immunohistochemical analysis of paraffin-embedded human cardiac muscle tissue labeling CLEC4C with ab239078 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) Ready to use.

Negative control : Negative staining in human cardiac muscle (PMID : 11748283).

Counter stained with hematoxylin.

Flow Cytometry - Anti-CLEC4C antibody [EPR21985] (AB239078)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-CLEC4C antibody [EPR21985] (AB239078)

Flow cytometric analysis of primary human peripheral blood mononuclear cell (PBMC) labeling CLEC4C with ab239078 at 1/60 dilution (right panel) compared with a Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab172730) (left panel). Goat Anti-Rabbit IgG Fc (Dylight^® 488) (ab98462) at 1/2000 dilution was used as the secondary antibody.

Gated on viable cells.

Note : CLEC4C and CD303 are alternative names for the same target.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC4C antibody [EPR21985] (AB239078)

Immunohistochemical analysis of paraffin-embedded human tonsil tissue labeling CLEC4C with ab239078 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) Ready to use. Membranous staining in plasmacytoid dendritic cells (PDCs) of human tonsil (PMID : 23847189, PMID : 11748283). Counter stained with hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) Ready to use.

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR21985

アイソタイプ

IgG

キャリアフリー

交差種

Human

アプリケーション

IHC-P, Flow Cyt

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/60", "FlowCyt-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000", "IHCP-species-notes": "" }, "Mouse": { "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "1/1000", "IHCP-species-notes": "" }, "Rat": { "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "1/1000", "IHCP-species-notes": "" } } }

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製品の詳細

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein A

バッファー組成

Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

出荷温度

Conditional Ambient

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells (PubMed : 11748283, PubMed : 21880719, PubMed : 25995448). Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man (PubMed : 21880719, PubMed : 25995448). Binds to serum IgG (PubMed : 25995448). Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells (PubMed : 11748283). May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells (PubMed : 11748283, PubMed : 21880719). May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium (PubMed : 11748283).

See full target information CLEC4C

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文献 (4)

Recent publications for all applications. Explore the full list and refine your search

The Journal of experimental medicine 222: PubMed40227192

2025

Enhanced TLR7-dependent production of type I interferon by pDCs underlies pandemic chilblains.

Applications

Unspecified application

Species

Unspecified reactive species

Fanny Saidoune,Danyel Lee,Jeremy Di Domizio,Corentin Le Floc'h,Raphael Jenelten,Jérémie Le Pen,Vincent Bondet,Ana Joncic,Marie-Anne Morren,Vivien Béziat,Shen-Ying Zhang,Emmanuelle Jouanguy,Darragh Duffy,Charles M Rice,Curdin Conrad,Jacques Fellay,Jean-Laurent Casanova,Michel Gilliet,Ahmad Yatim

Nature communications 15:8690 PubMed39375367

2024

Single-cell RNA sequencing reveals the pro-inflammatory roles of liver-resident Th1-like cells in primary biliary cholangitis.

Applications

Unspecified application

Species

Unspecified reactive species

Ciliang Jin,Penglei Jiang,Zhaoru Zhang,Yingli Han,Xue Wen,Lin Zheng,Wei Kuang,Jiangshan Lian,Guodong Yu,Xinyue Qian,Yue Ren,Miaomiao Lu,Lingling Xu,Weixin Chen,Jiyang Chen,Yuwei Zhou,Jinxia Xin,Ben Wang,Xi Jin,Pengxu Qian,Yida Yang

MedComm 5:e561 PubMed38721005

2024

PA28γ induces dendritic cell maturation and activates T-cell immune responses in oral lichen planus.

Applications

Unspecified application

Species

Unspecified reactive species

Yimei Wang,Qiyue Zhang,Xiaoting Deng,Ying Wang,Xin Tian,Shiyu Zhang,Yingqiang Shen,Xikun Zhou,Xin Zeng,Qianming Chen,Lu Jiang,Jing Li

Genome medicine 15:14 PubMed36869384

2023

Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing.

Applications

Unspecified application

Species

Unspecified reactive species

Junjie Hu,Lele Zhang,Haoran Xia,Yilv Yan,Xinsheng Zhu,Fenghuan Sun,Liangdong Sun,Shuangyi Li,Dianke Li,Jin Wang,Ya Han,Jing Zhang,Dongliang Bian,Huansha Yu,Yan Chen,Pengyu Fan,Qiang Ma,Gening Jiang,Chenfei Wang,Peng Zhang

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-CLEC4C 抗体 [EPR21985]

Anti-CLEC4C antibody [EPR21985]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC4C antibody [EPR21985] (AB239078)

Flow Cytometry - Anti-CLEC4C antibody [EPR21985] (AB239078)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC4C antibody [EPR21985] (AB239078)

関連する標識済み抗体及び組成の異なる製品 (9)

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

組合せ製品

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

製品の詳細

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (4)

Abcam product promise