Anti-CLEC-2 抗体 (ab81983)
Key features and details
- Goat polyclonal to CLEC-2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CLEC-2 antibody
CLEC-2 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to CLEC-2 -
由来種
Goat -
特異性
ab81983 is expected to recognize both reported isoforms (NP_001092901.1; NP_057593.3) -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human CLEC-2 aa 95-108 (internal sequence). (NP_001092901.1; NP_057593.3)
Sequence:KGHKCSPCDTNWRY
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ポジティブ･コントロール
- Human bone marrow and human kidney lysates.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 0.5% Tris buffered saline -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab81983の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 27 kDa.
1 hour primary incubation is recommended for this product. |
| 特記事項 |
|---|
|
WB
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 27 kDa. 1 hour primary incubation is recommended for this product. |
ターゲット情報
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機能
Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. -
組織特異性
Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets. -
配列類似性
Contains 1 C-type lectin domain. -
翻訳後修飾
Glycosylated.
Phosphorylated on tyrosine residue in response to rhodocytin binding. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 51266 Human
- Omim: 606783 Human
- SwissProt: Q9P126 Human
- Unigene: 409794 Human
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別名
- 1810061I13Rik antibody
- C type lectin domain family 1 member B antibody
- C type lectin like receptor 2 antibody
see all
画像
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Western blot - Anti-CLEC-2 antibody (ab81983)Anti-CLEC-2 antibody (ab81983) at 1 µg/ml + human kidney lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 27 kDa
Observed band size: 30 kDa why is the actual band size different from the predicted?
Exposure time: 1 hour
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab81983 は論文での使用が確認できていません。