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リコンビナントRabMAb

Anti-CINP 抗体 [EPR14446] (ab180955)

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Immunoprecipitation - Anti-CINP antibody [EPR14446] (ab180955)
  • Western blot - Anti-CINP antibody [EPR14446] (ab180955)
  • Anti-CINP antibody [EPR14446] (ab180955)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR14446] to CINP
  • Suitable for: WB, IP
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Carrier Free

製品の概要

  • 製品名

    Anti-CINP antibody [EPR14446]
    CINP 一次抗体 製品一覧

  • 製品の詳細

    Rabbit monoclonal [EPR14446] to CINP

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: WB, IPmore details

  • 種交差性

    交差種: Human
    交差が予測される動物種: Mouse, Rat

  • 免疫原

    Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

  • ポジティブ･コントロール

    • Jurkat, HeLa, 293 and MCF7 cell lysates.

  • 特記事項

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

製品の特性

  • 製品の状態

    Liquid

  • 保存方法

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • バッファー

    Preservative: 0.01% Sodium azide
    Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
  • Concentration information loading...

  • 精製度

    Tissue culture supernatant

  • ポリ/モノ

    モノクローナル

  • クローン名

    EPR14446

  • アイソタイプ

    IgG

  • 研究分野

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab180955の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
WB
1/1000 - 1/10000. Detects a band of approximately 26 kDa (predicted molecular weight: 24 kDa).
IP
1/60.
特記事項
WB
1/1000 - 1/10000. Detects a band of approximately 26 kDa (predicted molecular weight: 24 kDa).
IP
1/60.

ターゲット情報

  • 機能

    Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling.

  • 配列類似性

    Belongs to the CINP family.

  • 翻訳後修飾

    Phosphorylated by CDC7 but not by CDK2.

  • 細胞内局在

    Nucleus. Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication.
  • Information by UniProt

  • 参照データベース

    • 別名

      • CDK2-interacting protein antibody
      • CINP antibody
      • CINP protein antibody
      • CINP_HUMAN antibody
      • Cyclin dependent kinase 2 interacting protein antibody
      • Cyclin-dependent kinase 2-interacting protein antibody
      • MGC849 antibody
      see all

    画像

    • Immunoprecipitation - Anti-CINP antibody [EPR14446] (ab180955)
      Immunoprecipitation - Anti-CINP antibody [EPR14446] (ab180955)

      Western Blot analysis of 293 cell lysate immunoprecipitated with ab180955 at 1/60 dilution (Lane 1). Lane 2: Negative control. Anti-Rabbit IgG (HRP) secondary antibody, specific to the non-reduced form of IgG used at 1/500 dilution.

    • Western blot - Anti-CINP antibody [EPR14446] (ab180955)
      Western blot - Anti-CINP antibody [EPR14446] (ab180955)
      All lanes : Anti-CINP antibody [EPR14446] (ab180955) at 1/5000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : 293 cell lysate
      Lane 4 : MCF7 cell lysate

      Lysates/proteins at 20 µg per lane.

      Secondary
      All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

      Predicted band size: 24 kDa
      Observed band size: 26 kDa why is the actual band size different from the predicted?

    • Anti-CINP antibody [EPR14446] (ab180955)
      Anti-CINP antibody [EPR14446] (ab180955)

    参考文献 (0)

    ab180955 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab180955 は論文での使用が確認できていません。

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