Anti-CGRP 抗体 (ab36001)
Key features and details
- Goat polyclonal to CGRP
- Suitable for: ELISA, IHC-Fr, IHC-FoFr, IHC-P
- Reacts with: Mouse, Rat
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-CGRP antibody
CGRP 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to CGRP -
由来種
Goat -
特異性
Antibody is thought to react with whole molecule (1-37) and 23-37 fragment (C term). Specifically visualises CGRP in brain cells. -
アプリケーション
適用あり: ELISA, IHC-Fr, IHC-FoFr, IHC-Pmore details
適用なし: IHC-R -
種交差性
交差種: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
Purified Ig by Ammonium Sulphate fractionation. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab36001の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ELISA |
1/500 - 1/2500.
|
|
IHC-Fr | (4) |
1/200 - 1/3000.
|
IHC-FoFr | (2) |
1/200 - 1/3000. PubMed: 19805319
|
IHC-P | (5) |
1/200 - 1/3000.
|
特記事項 |
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ELISA
1/500 - 1/2500. |
IHC-Fr
1/200 - 1/3000. |
IHC-FoFr
1/200 - 1/3000. PubMed: 19805319 |
IHC-P
1/200 - 1/3000. |
ターゲット情報
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関連性
CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. -
細胞内局在
Endoplasmic reticulum and Secreted -
参照データベース
- Entrez Gene: 116903 Mouse
- Entrez Gene: 12310 Mouse
- Entrez Gene: 171519 Rat
- Entrez Gene: 24241 Rat
- SwissProt: P70160 Mouse
- SwissProt: Q99JA0 Mouse
- SwissProt: P01256 Rat
- SwissProt: P01257 Rat
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別名
- Calcitonin/calcitonin related polypeptide alpha antibody
- Alpha type CGRP antibody
- Beta type CGRP antibody
see all
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (143)
ab36001 は 143 報の論文で使用されています。
- Pei F et al. Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis. Nat Commun 14:344 (2023). PubMed: 36670126
- Albisetti GW et al. Inhibitory Kcnip2 neurons of the spinal dorsal horn control behavioral sensitivity to environmental cold. Neuron 111:92-105.e5 (2023). PubMed: 36323322
- Nakanishi S et al. Histological study on regional specificity of the mucosal nerve network in the rat large intestine. J Vet Med Sci 85:123-134 (2023). PubMed: 36517005
- Han X et al. Bioactive semaphorin 3A promotes sequential formation of sensory nerve and type H vessels during in situ osteogenesis. Front Bioeng Biotechnol 11:1138601 (2023). PubMed: 36949886
- Zhang H et al. Maintaining hypoxia environment of subchondral bone alleviates osteoarthritis progression. Sci Adv 9:eabo7868 (2023). PubMed: 37018403