Anti-CEP170 抗体 (ab84545)
Key features and details
- Rabbit polyclonal to CEP170
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CEP170 antibody
CEP170 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CEP170 -
由来種
Rabbit -
アプリケーション
適用あり: ICC/IFmore details -
種交差性
交差種: Human
交差が予測される動物種: Rabbit, Cow, Chimpanzee
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免疫原
Synthetic peptide within Human CEP170 aa 1500 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. NP_055627.2
Database link: Q5SW79 -
ポジティブ･コントロール
- HeLa cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab84545の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF |
1/100 - 1/500. Permeabilization with Triton-X 100 is recommended.
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| 特記事項 |
|---|
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ICC/IF
1/100 - 1/500. Permeabilization with Triton-X 100 is recommended. |
ターゲット情報
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関連性
CEP170, centrosomal protein 170kDa, plays a role in microtubule organization. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. -
細胞内局在
Centrosome, centriole. Cytoplasm, cytoskeleton. Associated with the mature mother centriole. Associated with spindle microtubules during mitosis. -
参照データベース
- Entrez Gene: 9859 Human
- SwissProt: Q5SW79 Human
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別名
- XRCC5 binding protein antibody
- 4933426L22Rik antibody
- A330004A13Rik antibody
see all
画像
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Immunocytochemistry/ Immunofluorescence - Anti-CEP170 antibody (ab84545)Detection of Human CEP170 by Immunocytochemistry.
Sample: NBF-fixed asynchronous HeLa cells.Antibody: ab84545 used at a dilution of 1/100.
Detection: Red-fluorescent Alexa Fluor 594 goat anti-rabbit IgG. -
Immunocytochemistry/ Immunofluorescence - Anti-CEP170 antibody (ab84545)Detection of Human CEP170 by Immunocytochemistry.
Sample: NBF-fixed asynchronous HeLa cells.Antibody: ab84545 used at a dilution of 1/100.
Detection: Red-fluorescent Alexa Fluor 594 goat anti-rabbit IgG.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab84545 は 3 報の論文で使用されています。
- Jerby-Arnon L et al. A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade. Cell 175:984-997.e24 (2018). PubMed: 30388455
- Abdul-Sater Z et al. FANCA safeguards interphase and mitosis during hematopoiesis in vivo. Exp Hematol 43:1031-1046.e12 (2015). IF . PubMed: 26366677
- Hossain M & Stillman B Meier-Gorlin syndrome mutations disrupt an Orc1 CDK inhibitory domain and cause centrosome reduplication. Genes Dev 26:1797-810 (2012). PubMed: 22855792