Anti-Cell adhesion molecule 2 抗体 (ab64873)
Key features and details
- Rabbit polyclonal to Cell adhesion molecule 2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Cell adhesion molecule 2 antibody -
製品の詳細
Rabbit polyclonal to Cell adhesion molecule 2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide (Human)
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol, 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab64873の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa).
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| 特記事項 |
|---|
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WB
1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa). |
ターゲット情報
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配列類似性
Belongs to the nectin family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 253559 Human
- Omim: 609938 Human
- SwissProt: Q8N3J6 Human
- Unigene: 164578 Human
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別名
- CADM2 antibody
- CADM2_HUMAN antibody
- Cell adhesion molecule 2 antibody
see all
画像
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Western blot - Anti-Cell adhesion molecule 2 antibody (ab64873)All lanes : Anti-Cell adhesion molecule 2 antibody (ab64873) at 1/500 dilution
Lane 1 : Extracts from HepG2 cells
Lane 2 : Extracts from HepG2 cells with immunizing peptide at 5 µg
Lysates/proteins at 10 µg per lane.
Predicted band size: 48 kDa
Observed band size: 48 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (7)
ab64873 は 7 報の論文で使用されています。
- Jinyang M et al. Long Non-Coding RNA HCG11 Inhibits Glioma Cells Proliferation and Migration through Decoying miR-590-3p and Up-Regulating CADM2. Pathobiology 89:233-244 (2022). PubMed: 35279660
- Peng G et al. MicroRNA-25 promotes cell proliferation, migration and invasion in glioma by directly targeting cell adhesion molecule 2. Exp Ther Med 23:16 (2022). PubMed: 34815768
- He J et al. Long Noncoding MAGI2-AS3 Suppresses Several Cellular Processes of Lung Squamous Cell Carcinoma Cells by Regulating miR-374a/b-5p/CADM2 Axis. Cancer Manag Res 12:289-302 (2020). PubMed: 32021443
- Liu N et al. CADM2 inhibits human glioma proliferation, migration and invasion. Oncol Rep 41:2273-2280 (2019). PubMed: 30816549
- Huang YX et al. Downregulation of microRNA-182 inhibits cell viability, invasion and angiogenesis in retinoblastoma through inhibition of the PI3K/AKT pathway and CADM2 upregulation. Int J Oncol 53:2615-2626 (2018). PubMed: 30320366
- Liu Y et al. MicroRNA-125a-3p is involved in early behavioral disorders in stroke-afflicted rats through the regulation of Cadm2. Int J Mol Med 40:1851-1859 (2017). PubMed: 29039453
- Galuska SP et al. Synaptic cell adhesion molecule SynCAM 1 is a target for polysialylation in postnatal mouse brain. Proc Natl Acad Sci U S A 107:10250-5 (2010). ICC/IF ; Mouse . PubMed: 20479255