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AB74045

Anti-CEBPG 抗体

Anti-CEBPG antibody

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(5 Publications)

Rabbit Polyclonal CEBPG antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human CEBPG.

別名を表示する

CCAAT/enhancer-binding protein gamma, C/EBP gamma, CEBPG

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CEBPG antibody (AB74045)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CEBPG antibody (AB74045)

Immunohistochemistry analysis of paraffin-embedded human heart tissue using ab74045, at 1/50 dilution, in the presence (right panel) or absence (left panel) of immunising peptide.

Western blot - Anti-CEBPG antibody (AB74045)
  • WB

Unknown

Western blot - Anti-CEBPG antibody (AB74045)

All lanes:

Western blot - Anti-CEBPG antibody (ab74045) at 1/500 dilution

Lane 1:

Extracts from RAW264.7 cells at 5 µg

Lane 2:

Extracts from RAW264.7 cells at 5 µg with immunising peptide

Predicted band size: 16 kDa

Observed band size: 21 kDa

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Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse, Human

アプリケーション

WB, IHC-P

applications

免疫原

Synthetic Peptide within Human CEBPG. The exact immunogen used to generate this antibody is proprietary information.

P53567

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/100", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
バッファー組成
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
保管に関する情報
Stable for 12 months at -20°C
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The CCAAT/enhancer-binding protein gamma (CEBPG) also known as C/EBPγ is a transcription factor that regulates gene expression by binding to DNA. It weighs approximately 18-19 kDa. CEBPG is expressed in various tissues including liver lung and adipose tissue. This broad expression pattern suggests CEBPG interacts with cellular processes across different physiological contexts.
Biological function summary

CEBPG serves as a regulator of cellular differentiation and proliferation. It often forms dimers with other C/EBP family members enhancing its DNA binding capacity and functional diversity. By participating in these complexes CEBPG helps maintain homeostasis and regulate immune responses. Its activity is vital for controlling genes involved in metabolism and inflammation.

Pathways

CEBPG functions within the MAPK signaling pathway and the IL-6 signaling pathway. In the MAPK pathway it interacts with proteins such as JNK thereby influencing cell growth and apoptosis. In the IL-6 pathway CEBPG contributes to the modulation of the inflammatory response. This involvement makes CEBPG a significant player in immune function and cellular stress responses.

CEBPG has relevance to conditions like leukemia and chronic inflammatory diseases. Alterations in CEBPG expression or function can disrupt normal cell cycle control linking it to oncogenesis. In leukemia CEBPG interacts with proteins such as CEBPA influencing hematopoietic stem cell differentiation. In chronic inflammatory diseases CEBPG’s role in regulating inflammatory pathways can exacerbate or mitigate disease symptoms.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Transcription factor that binds to the promoter and the enhancer regions of target genes. Binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene (PubMed : 7665092). Binds to the promoter and the enhancer of the immunoglobulin heavy chain. Binds to GPE1, a cis-acting element in the G-CSF gene promoter.
See full target information CEBPG
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文献 (5)

Recent publications for all applications. Explore the full list and refine your search

Molecular cancer therapeutics 21:1632-1644 PubMed36121385

2022

Anticancer Activity of ST101, A Novel Antagonist of CCAAT/Enhancer Binding Protein β.

Applications

Unspecified application

Species

Unspecified reactive species

Emad Darvishi,Lila Ghamsari,Siok F Leong,Ricardo Ramirez,Mark Koester,Erin Gallagher,Miao Yu,Jody M Mason,Gene Merutka,Barry J Kappel,Jim A Rotolo

Nucleic acids research 50:7298-7309 PubMed35801910

2022

Systemic approaches using single cell transcriptome reveal that C/EBPγ regulates autophagy under amino acid starved condition.

Applications

Unspecified application

Species

Unspecified reactive species

Dongha Kim,Junil Kim,Young Suk Yu,Yong Ryoul Kim,Sung Hee Baek,Kyoung-Jae Won

The Journal of biological chemistry 295:2787-2803 PubMed31953319

2020

Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ.

Applications

Unspecified application

Species

Unspecified reactive species

Scott M Ebert,Steven A Bullard,Nathan Basisty,George R Marcotte,Zachary P Skopec,Jason M Dierdorff,Asma Al-Zougbi,Kristin C Tomcheck,Austin D DeLau,Jacob A Rathmacher,Sue C Bodine,Birgit Schilling,Christopher M Adams

Molecular cancer research : MCR 18:216-228 PubMed31676720

2019

Dominant-Negative ATF5 Compromises Cancer Cell Survival by Targeting CEBPB and CEBPD.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaotian Sun,Parvaneh Jefferson,Qing Zhou,James M Angelastro,Lloyd A Greene

Oncotarget 8:114195-114209 PubMed29371979

2017

ETV4 collaborates with Wnt/β-catenin signaling to alter cell cycle activity and promote tumor aggressiveness in gastrointestinal stromal tumor.

Applications

Unspecified application

Species

Unspecified reactive species

Shan Zeng,Adrian M Seifert,Jennifer Q Zhang,Teresa S Kim,Timothy G Bowler,Michael J Cavnar,Benjamin D Medina,Gerardo A Vitiello,Ferdinand Rossi,Jennifer K Loo,Nesteene J Param,Ronald P DeMatteo
View all publications
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