Anti-CEACAM19 抗体 [HY-8H10] (ab59717)
![Flow Cytometry - Anti-CEACAM19 antibody [HY-8H10] (ab59717)](https://www.abcam.co.jp/ps/products/59/ab59717/Images/ab59717_1.jpg "Flow Cytometry - Anti-CEACAM19 antibody [HY-8H10] (ab59717)")
Key features and details
- Mouse monoclonal [HY-8H10] to CEACAM19
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-CEACAM19 antibody [HY-8H10] -
製品の詳細
Mouse monoclonal [HY-8H10] to CEACAM19 -
由来種
Mouse -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Genetic immunisation with cDNA encoding human CEACAM19.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
HY-8H10 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab59717の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
| 特記事項 |
|---|
Flow Cyt: Use 1.2µg for 106 cells.
SDS-PAGE: Use 2µg.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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関連性
CEACAM19 belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a putative glycoprotein which is membrane-bound via a transmembrane domain. Like all members of the CEACAM family, the CEACAM19 protein is a single-pass type I membrane protein and consists of a single extracellular N domain. CEACAM19 expression is ubiquitous with highest expression in prostate, uterus, fetal brain, mammary gland, adrenal gland, skeletal muscle, small intestine, and kidney. -
細胞内局在
Cell Membrane; Single-pass type I membrane protein . -
参照データベース
- Entrez Gene: 56971 Human
- Omim: 606691 Human
- SwissProt: Q7Z692 Human
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別名
- Carcinoembryonic antigen like 1 antibody
- Carcinoembryonic antigen related cell adhesion molecule 19 antibody
- CEA related cell adhesion molecule 19 antibody
see all
画像
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Flow Cytometry - Anti-CEACAM19 antibody [HY-8H10] (ab59717)BOSC23 cells were transiently trans-fected with an expression vector encoding either CEACAM19 (red curve) or an irrelevant protein (control transfectant). Binding of ab59717 was detected with a PE conjugated secondary antibody. A positive signal was obtained only with CEACAM19 transfected cells.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab59717 は 1 報の論文で使用されています。
- Kobayashi M et al. Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma. Br J Cancer 107:1745-53 (2012). PubMed: 23099808
