Anti-CDCA3 抗体 - C-terminal (ab167037)
Key features and details
- Rabbit polyclonal to CDCA3 - C-terminal
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CDCA3 antibody - C-terminal -
製品の詳細
Rabbit polyclonal to CDCA3 - C-terminal -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- Human placenta tissue; HepG2 cell extract.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20ºC. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
PBS without Mg2+ and Ca2+. -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab167037の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 29 kDa.
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| IHC-P |
Use a concentration of 5 µg/ml.
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| 特記事項 |
|---|
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WB
1/500 - 1/1000. Predicted molecular weight: 29 kDa. |
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IHC-P
Use a concentration of 5 µg/ml. |
ターゲット情報
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関連性
CDCA3 (Cell division cycle associated 3) is an F-box-like protein which is required for entry into mitosis. It is associated with SKP1 as part of a SCF (SKP1-cullin-F-box) protein ligase complex, and is required for the ubiquitination and degradation of the CDK1 inhibitory tyrosine kinase WEE1 at G2/M phase. -
細胞内局在
Cytoplasmic. Cytosol. -
参照データベース
- Entrez Gene: 83461 Human
- Omim: 607749 Human
- SwissProt: Q99618 Human
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別名
- C8 antibody
- CDCA 3 antibody
- Cell division cycle associated 3 antibody
see all
画像
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Western blot - Anti-CDCA3 antibody - C-terminal (ab167037)All lanes : Anti-CDCA3 antibody - C-terminal (ab167037) at 1/500 dilution
Lane 1 : HepG2 cell extract
Lane 2 : HepG2 cell extract with immunizing peptide
Predicted band size: 29 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDCA3 antibody - C-terminal (ab167037)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue labeling CDCA3 with ab167037 at 5 µg/ml.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab167037 は 4 報の論文で使用されています。
- Qiao Y et al. Long noncoding RNA ST8SIA6-AS1 promotes cell proliferation and metastasis in triple-negative breast cancer by targeting miR-145-5p/CDCA3 to inactivate the p53/p21 signaling pathway. Environ Toxicol 37:2398-2411 (2022). PubMed: 35730485
- Zhang Y et al. CDCA3 is a potential prognostic marker that promotes cell proliferation in gastric cancer. Oncol Rep 41:2471-2481 (2019). PubMed: 30816466
- Qian W et al. CDCA3 mediates p21-dependent proliferation by regulating E2F1 expression in colorectal cancer. Int J Oncol 53:2021-2033 (2018). PubMed: 30226575
- Zhang Y et al. Transcriptome Landscape of Human Folliculogenesis Reveals Oocyte and Granulosa Cell Interactions. Mol Cell 72:1021-1034.e4 (2018). PubMed: 30472193