AB23894

Anti-CD90 / Thy1 抗体 [AF-9]

Name: Anti-CD90 / Thy1 抗体 [AF-9] (ab23894) | Abcam
Brand: Abcam Limited
SKU: AB23894
Price: 74000 JPY
Availability: InStock
Rating: 5 (1 reviews)

Anti-CD90 / Thy1 antibody [AF-9]

(1 Review)

(52 Publications)

Mouse Monoclonal CD90 / Thy1 antibody. Suitable for Flow Cyt and reacts with Human samples. Cited in 52 publications. Immunogen corresponding to Cell preparation containing THY1 protein.

別名を表示する

CD90, Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, THY1

1 Images

Flow Cytometry - Anti-CD90 / Thy1 antibody [AF-9] (AB23894)

Flow Cyt

Unknown

Flow Cytometry - Anti-CD90 / Thy1 antibody [AF-9] (AB23894)

Overlay histogram showing Jurkat cells stained with ab23894 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab23894, 1μg/1x10⁶ cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x10⁶ cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

AF-9

アイソタイプ

IgG1

キャリアフリー

交差種

Human

アプリケーション

Flow Cyt

applications

免疫原

Cell preparation containing THY1 protein. The exact immunogen used to generate this antibody is proprietary information.

P04216

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1 µg for 10^6 Cells", "FlowCyt-species-notes": "<p><a href='/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein G

バッファー組成

pH: 7.3 Preservative: 0.05% Sodium azide Constituents: PBS

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).

Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

See full target information THY1

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文献 (52)

Recent publications for all applications. Explore the full list and refine your search

Stem cell research & therapy 16:218 PubMed40312745

2025

Puerarin relives inflammation, bone destruction and facilitates osteogenic differentiation in periodontitis by enhancing mitochondrial autophagy via activating mitochondrial Mitofusin 2.

Applications

Unspecified application

Species

Unspecified reactive species

Yulan Xiang,Zelu Li,Xin He,Xiaoyang Chu,Chunyan Gao,Jiahao Guo,Yingyi Luan,Kai Yang,Dongliang Zhang

Biomolecules & biomedicine 25:869-882 PubMed39226107

2024

Forkhead box O-1 regulates the biological behavior of BMP-2-induced human bone mesenchymal stem cells through mitochondrial dynamics and autophagy.

Applications

Unspecified application

Species

Unspecified reactive species

Weijia Feng,Nannan Chen,Ke Chen,Ting Chen

Scientific reports 14:15732 PubMed38977826

2024

The dynamic expression of YAP is essential for the development of male germ cells derived from human embryonic stem cells.

Applications

Unspecified application

Species

Unspecified reactive species

Sujittra Khampang,Chanchao Lorthongpanich,Chuti Laowtammathron,Phatchanat Klaihmon,Sukanya Meesa,Wichuda Suksomboon,Nittaya Jiamvoraphong,Pakpoom Kheolamai,Sudjit Luanpitpong,Charles A Easley,Eisa Mahyari,Surapol Issaragrisil

Advanced materials (Deerfield Beach, Fla.) 36:e2304333 PubMed38096399

2023

Inflammation-Targeting Mesenchymal Stem Cells Combined with Photothermal Treatment Attenuate Severe Joint Inflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Min Jun Shin,Jun-Young Park,Jun Young Park,Su Hyun Lim,Hyoungsub Lim,Jin Kyeong Choi,Chul-Kyu Park,Youn Joo Kang,Dongwoo Khang

Biomolecules & biomedicine : PubMed38059910

2023

Mechanism of adipose tissue-derived stromal cell-extracellular vesicles in treating oral submucous fibrosis by blocking the TGF-β1/Smad3 pathway via the miR-760-3p/IGF1R axis

Applications

Unspecified application

Species

Unspecified reactive species

Fengcong Wang,Li Jiang,Ping Liu,Yanjun Jiang

Stem cell research & therapy 14:344 PubMed38031182

2023

The effect of TLR3 priming conditions on MSC immunosuppressive properties.

Applications

Unspecified application

Species

Unspecified reactive species

Tatiana Tolstova,Ekaterina Dotsenko,Peter Kozhin,Svetlana Novikova,Victor Zgoda,Alexander Rusanov,Nataliya Luzgina

Neural regeneration research 19:900-907 PubMed37843227

2023

Human umbilical cord mesenchymal stem cell-derived exosomes loaded into a composite conduit promote functional recovery after peripheral nerve injury in rats.

Applications

Unspecified application

Species

Unspecified reactive species

Haoshuai Tang,Junjin Li,Hongda Wang,Jie Ren,Han Ding,Jun Shang,Min Wang,Zhijian Wei,Shiqing Feng

Journal of cellular and molecular medicine 27:3526-3538 PubMed37698037

2023

Inhibitory role of bone marrow mesenchymal stem cells-derived exosome in non-small-cell lung cancer: microRNA-30b-5p, EZH2 and PI3K/AKT pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Tong Wu,Qi Tian,Ruiji Liu,Ke Xu,Shanshan Shi,Xiudi Zhang,Liming Gao,Xiaobo Yin,Shufeng Xu,Ping Wang

Biomedicines 11: PubMed37760805

2023

Cytocompatibility and Osteoinductive Properties of Collagen-Fibronectin Hydrogel Impregnated with siRNA Targeting Glycogen Synthase Kinase 3β: In Vitro Study.

Applications

Unspecified application

Species

Unspecified reactive species

Elena V Galitsyna,Anastasiia A Buianova,Vadim I Kozhukhov,Sergey P Domogatsky,Tatiana B Bukharova,Dmitriy V Goldshtein

Folia morphologica 83:72-82 PubMed36967622

2023

Biodegradable nanofiber coated human umbilical cord as nerve scaffold for sciatic nerve regeneration in albino Wistar rats.

Applications

Unspecified application

Species

Unspecified reactive species

Balasundari Ramesh,Jaikanth Chandrasekaran,Kotturathu Mammen Cherian,Adegbenro Omotuyi John Fakoya

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-CD90 / Thy1 抗体 [AF-9]

Anti-CD90 / Thy1 antibody [AF-9]

Flow Cytometry - Anti-CD90 / Thy1 antibody [AF-9] (AB23894)

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (52)

代替製品

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組合せ製品

Assay Kits

Secondary Antibodies

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Primary Antibodies

Primary Antibodies

Abcam product promise