Anti-CD69 抗体 [H1.2F3] (ab25190)
Key features and details
- Armenian Hamster monoclonal [H1.2F3] to CD69
- Suitable for: IHC-FoFr, Flow Cyt, IP, Cellular Activation
- Reacts with: Mouse
- Isotype: IgG
Related conjugates and formulations
製品の概要
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製品名
Anti-CD69 antibody [H1.2F3]
CD69 一次抗体 製品一覧 -
製品の詳細
Armenian Hamster monoclonal [H1.2F3] to CD69 -
由来種
Armenian hamster -
特異性
ab25190 recognises mouse CD69/Very Early Activation Antigen (VEA),. -
アプリケーション
適用あり: IHC-FoFr, Flow Cyt, IP, Cellular Activationmore details -
種交差性
交差種: Mouse -
免疫原
Tissue/ cell preparation (Mouse) - Y245 mouse dendritic epidermal T cell line.
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特記事項
This antibody augments PMA-induced T-cell proliferation, and induces redirected lysis of Fc receptor-bearing target cells by NK cells.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 8.2
Constituent: 100% Borate buffered saline -
Concentration information loading...
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精製度
Affinity purified -
一次抗体 備考
This antibody augments PMA-induced T-cell proliferation, and induces redirected lysis of Fc receptor-bearing target cells by NK cells. -
ポリ/モノ
モノクローナル -
クローン名
H1.2F3 -
アイソタイプ
IgG -
軽鎖の種類
lambda -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab25190の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-FoFr |
Use at an assay dependent concentration. PubMed: 22483694
|
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Flow Cyt |
Use at an assay dependent concentration.
Pubmed:2838547 and Pubmed:2026886. ab18474 - Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody. |
|
IP |
Use at an assay dependent concentration.
Please see: Pubmed:2838547. |
|
Cellular Activation |
Use at an assay dependent concentration.
T cell and NK cells. Please see: Pubmed:2838547 and Pubmed:2026886. |
特記事項 |
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IHC-FoFr
Use at an assay dependent concentration. PubMed: 22483694 |
Flow Cyt
Use at an assay dependent concentration. Pubmed:2838547 and Pubmed:2026886. ab18474 - Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody. |
IP
Use at an assay dependent concentration. Please see: Pubmed:2838547. |
Cellular Activation
Use at an assay dependent concentration. T cell and NK cells. Please see: Pubmed:2838547 and Pubmed:2026886. |
ターゲット情報
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機能
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. -
組織特異性
Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. -
配列類似性
Contains 1 C-type lectin domain. -
発生段階
Earliest inducible cell surface glycoprotein acquired during lymphoid activation. -
翻訳後修飾
Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 12515 Mouse
- SwissProt: P37217 Mouse
- Unigene: 74745 Mouse
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別名
- Activation inducer molecule (AIM/CD69) antibody
- Activation inducer molecule antibody
- AIM antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab25190 は 2 報の論文で使用されています。
- Aftabizadeh M et al. Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis. JCI Insight 6:N/A (2021). PubMed: 33491667
- Ishizaki S et al. Role of CD69 in acute lung injury. Life Sci 90:657-65 (2012). IHC-FoFr ; Mouse . PubMed: 22483694