Anti-CD66b 抗体 [GM-2H6] (ab48589)
![Flow Cytometry - Anti-CD66b antibody [GM-2H6] (ab48589)](https://www.abcam.co.jp/ps/products/48/ab48589/Images/ab48589-61080-anti-cd66b-antibody-gm-2h6-flow-cytometry.jpg "Flow Cytometry - Anti-CD66b antibody [GM-2H6] (ab48589)")
Key features and details
- Mouse monoclonal [GM-2H6] to CD66b
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-CD66b antibody [GM-2H6]
CD66b 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [GM-2H6] to CD66b -
由来種
Mouse -
特異性
This antibody exclusively recognizes CD66b (CEACAM8). -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
The complete extracellular region of human CD66b (CEACAM8) cDNA.
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ポジティブ･コントロール
- Flow Cyt: BOSC23 cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
The antibody was purified from cell culture supernatants. -
ポリ/モノ
モノクローナル -
クローン名
GM-2H6 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab48589の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
| 特記事項 |
|---|
ELISA: Use at an assay dependent dilution.
Flow Cyt: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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組織特異性
Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow. -
配列類似性
Belongs to the immunoglobulin superfamily. CEA family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 1088 Human
- Omim: 615747 Human
- SwissProt: P31997 Human
- Unigene: 41 Human
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別名
- Carcinoembryonic antigen CGM6 antibody
- Carcinoembryonic antigen gene family member 6 antibody
- Carcinoembryonic antigen related cell adhesion molecule 8 antibody
see all
画像
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Flow Cytometry - Anti-CD66b antibody [GM-2H6] (ab48589)Ab48589, staining CD66b (CEACAM8) by Flow Cytometry.
BOSC23 cells were transiently transfected with expression vectors containing either the cDNA of CEACAM1, CEACAM3-8 or PSG. The latter was expressed as a membrane bound fusion protein. Expression of the constructs was tested with monoclonal antibodies known to recognize the corresponding proteins (CEACAM1, 3, 4, 5 and 6: D14HD11; CEACAM7: BAC2; CEACAM8: Tet2; PSG: BAP3; green curves). An irrelevant monoclonal antibody served as a negative control (black curves). For specificity testing, ab48589 was tested on all CEACAM transfectants. A positive signal was obtained only with CEACAM8 (CD66b) transfected cells (red curve).
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab48589 は 1 報の論文で使用されています。
- Yoon J et al. CD66b Regulates Adhesion and Activation of Human Eosinophils. J Immunol 179:8454-62 (2007). Human . PubMed: 18056392