Anti-CD5L/CT-2 抗体 (ab45408)
Key features and details
- Rabbit polyclonal to CD5L/CT-2
- Suitable for: IHC-P, ICC/IF, WB
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-CD5L/CT-2 antibody
CD5L/CT-2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CD5L/CT-2 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, ICC/IF, WBmore details -
種交差性
交差種: Mouse, Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- Human Lymph Node Tissue Lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab45408の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use a concentration of 2 µg/ml.
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| ICC/IF |
Use a concentration of 20 µg/ml.
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| WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 38 kDa).
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| 特記事項 |
|---|
|
IHC-P
Use a concentration of 2 µg/ml. |
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ICC/IF
Use a concentration of 20 µg/ml. |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 38 kDa). |
ターゲット情報
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機能
May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis. -
組織特異性
Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver, but not in non-lymphoid tissues. -
配列類似性
Contains 3 SRCR domains. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 922 Human
- Entrez Gene: 11801 Mouse
- Omim: 602592 Human
- SwissProt: O43866 Human
- SwissProt: Q9QWK4 Mouse
- Unigene: 134035 Human
- Unigene: 6676 Mouse
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別名
- AAC-11 antibody
- AIM antibody
- API6 antibody
see all
画像
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Western blot - Anti-CD5L/CT-2 antibody (ab45408)Lane 1 : Anti-CD5L/CT-2 antibody (ab45408) at 1 µg/ml
Lane 2 : Anti-CD5L/CT-2 antibody (ab45408) at 2 µg/ml
Lane 3 : Anti-CD5L/CT-2 antibody (ab45408) at 4 µg/ml
All lanes : human lymph node tissue lysate
Predicted band size: 38 kDa
Observed band size: 46 kDa why is the actual band size different from the predicted? -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD5L/CT-2 antibody (ab45408)ab45408 at 2µg/ml staining CD5L/CT-2 in human lymph node tissue by IHC
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Immunocytochemistry/ Immunofluorescence - Anti-CD5L/CT-2 antibody (ab45408)Immunofluorescence of AIM in Human Lymph Node cells using ab45408 at 20 ug/ml.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (14)
ab45408 は 14 報の論文で使用されています。
- Gao Z et al. Role of CD5 molecular-like on hepatocellular carcinoma. Chin Med J (Engl) 136:556-564 (2023). PubMed: 36939243
- Qu J et al. Characterization and clinical verification of immune-related genes in hepatocellular carcinoma to aid prognosis evaluation and immunotherapy. BMC Cancer 23:549 (2023). PubMed: 37322434
- Zoia M et al. Validation of Effective Extracellular Vesicles Isolation Methods Adapted to Field Studies in Malaria Endemic Regions. Front Cell Dev Biol 10:812244 (2022). PubMed: 35652104
- Watanabe Y et al. Extracellular vesicles derived from GMSCs stimulated with TNF-α and IFN-α promote M2 macrophage polarization via enhanced CD73 and CD5L expression. Sci Rep 12:13344 (2022). PubMed: 35922474
- Gualdrón-López M et al. Mass Spectrometry Identification of Biomarkers in Extracellular Vesicles From Plasmodium vivax Liver Hypnozoite Infections. Mol Cell Proteomics 21:100406 (2022). PubMed: 36030044