Anti-CD5 抗体 [CD5/2416] - BSA and Azide free
Anti-CD5 antibody [CD5/2416] - BSA and Azide free
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(1 Publication)
Mouse Monoclonal CD5 antibody. Carrier free. Suitable for IHC-P, WB, Protein Array and reacts with Human, Recombinant full length protein - Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CD5 aa 250-400.
別名を表示する
CD5, LEU1, T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD5 antibody [CD5/2416] - BSA and Azide free (AB237940)
Formalin-fixed, paraffin-embedded human tonsil tissue stained for CD5 using ab237940 at 2 μg/ml in immunohistochemical analysis.
- WB
Supplier Data
Western blot - Anti-CD5 antibody [CD5/2416] - BSA and Azide free (AB237940)
All lanes:
Western blot - Anti-CD5 antibody [CD5/2416] (<a href='/products/primary-antibodies/cd5-antibody-cd5-2416-ab238086'>ab238086</a>) at 2 µg/mL
All lanes:
Jurkat (human T cell leukemia cell line from peripheral blood) cell lysate
Predicted band size: 54 kDa
false
- Protein Array
Unknown
Protein Array - Anti-CD5 antibody [CD5/2416] - BSA and Azide free (AB237940)
This data was produced with ab238086, the same antibody in a different formulation with BSA and Azide.
ab238086 was tested in protein array against over 19000 different full-length human proteins.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Reactivity data
出荷温度及び保存条件
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精製方法
精製に関する特記事項
バッファー組成
出荷温度
短期保存期間
短期保存温度
長期保存温度
分注に関する情報
保管に関する情報
補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
CD5 is essential in the immune system's ability to maintain tolerance to self-antigens thereby preventing autoimmune responses. CD5 forms part of a receptor complex on the cell surface that interacts with ligands and other receptors to fine-tune immune cell signaling. Its localization and function in T cells relate closely to its ability to modulate signaling pathways essential for cell survival and proliferation. This modulation is important for ensuring that immune responses are appropriate to the stimuli encountered.
Pathways
CD5 is involved in signal transduction processes important for immune tolerance and modulation. It intersects with pathways like the T cell receptor (TCR) signaling pathway and the NF-kB signaling pathway. These pathways involve interaction with proteins like Zap70 a tyrosine kinase related to TCR signaling and the downstream activation of transcription factors that regulate immune responses. The protein CRIS1 also appears in some pathway interactions highlighting the interconnected nature of immune regulatory proteins.
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ターゲットの情報
文献 (1)
Recent publications for all applications. Explore the full list and refine your search
Veterinary sciences 8: PubMed34941853
2021
Applications
Unspecified application
Species
Unspecified reactive species
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