Anti-CD45RC 抗体 [MIL15] (ab14125)
Key features and details
- Mouse monoclonal [MIL15] to CD45RC
- Suitable for: Flow Cyt
- Reacts with: Pig
- Isotype: IgM
製品の概要
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製品名
Anti-CD45RC antibody [MIL15]
CD45RC 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [MIL15] to CD45RC -
由来種
Mouse -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Pig -
免疫原
Full length native protein (purified) (Pig). (Cells isolated from porcine mesenteric lymph node).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: Tissue culture supernatant, 1.72% Tris HCl, 10% Fetal calf serum -
Concentration information loading...
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精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
MIL15 -
アイソタイプ
IgM -
研究分野
関連製品
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Compatible Secondaries
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab14125の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt |
Use 10µl for 106 cells.
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特記事項 |
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Flow Cyt
Use 10µl for 106 cells. |
ターゲット情報
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機能
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. -
関連疾患
Severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive
Multiple sclerosis -
配列類似性
Belongs to the protein-tyrosine phosphatase family. Receptor class 1/6 subfamily.
Contains 2 fibronectin type-III domains.
Contains 2 tyrosine-protein phosphatase domains. -
ドメイン
The first PTPase domain interacts with SKAP1. -
翻訳後修飾
Heavily N- and O-glycosylated. -
細胞内局在
Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts. - Information by UniProt
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別名
- B220 antibody
- CD45 antibody
- CD45R antibody
see all
画像
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Figure A. FITC conjugated mouse anti porcine CD3 and purified mouse IgM isotype control detected with goat anti mouse IgM PE.
Figure B. FITC conjugated mouse anti porcine CD3 and purified mouse Anti-CD45RC antibody [MIL15] (ab14125) detected with goat anti mouse IgM.
All experiments performed on red cell lysed porcine blood gated on mononuclear cells.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab14125 は論文での使用が確認できていません。