Anti-CD40 抗体 [1C10] (ab25298)
Key features and details
- Rat monoclonal [1C10] to CD40
- Suitable for: Flow Cyt, IP
- Reacts with: Mouse
- Isotype: IgG2a
Related conjugates and formulations
製品の概要
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製品名
Anti-CD40 antibody [1C10]
CD40 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [1C10] to CD40 -
由来種
Rat -
アプリケーション
適用あり: Flow Cyt, IPmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant fragment corresponding to CD40. sCD40
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 8.20
Constituent: 100% Borate buffered saline -
Concentration information loading...
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精製度
Affinity purified -
ポリ/モノ
モノクローナル -
クローン名
1C10 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab25298の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
|
特記事項 |
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Flow Cyt
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
ターゲット情報
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機能
Receptor for TNFSF5/CD40LG. -
組織特異性
B-cells and in primary carcinomas. -
関連疾患
Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation. -
配列類似性
Contains 4 TNFR-Cys repeats. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 21939 Mouse
- SwissProt: P27512 Mouse
- Unigene: 271833 Mouse
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別名
- AI326936 antibody
- B cell associated molecule CD40 antibody
- B cell surface antigen CD40 antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab25298 は 1 報の論文で使用されています。
- Heath AW et al. Monoclonal antibodies to murine CD40 define two distinct functional epitopes. Eur J Immunol 24:1828-34 (1994). PubMed: 7519997