AB33775

Anti-CD4 抗体 [OX-35]

Anti-CD4 antibody [OX-35]

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(11 Publications)

Mouse Monoclonal CD4 antibody. Suitable for Flow Cyt and reacts with Rat samples. Cited in 11 publications. Immunogen corresponding to Cell preparation containing Cd4 protein.

別名を表示する

CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, W3/25 antigen, Cd4

2 Images

Flow Cytometry - Anti-CD4 antibody [OX-35] (AB33775)

Flow Cyt

Unknown

Flow Cytometry - Anti-CD4 antibody [OX-35] (AB33775)

Flow cytometric analysis using surface staining of rat splenocyte suspension. Rat splenocytes are stained using 1.6μg/ml ab33775 anti-rat CD4, GAM PE, (red) and are separated from REH cells stained with 1.6μg/ml mouse isotype control purified antibody

Flow Cyt

Supplier Data

Flow Cytometry - Anti-CD4 antibody [OX-35] (AB33775)

Surface staining flow cytometric pattern of rat splenocytes stained with 1.6μg/ml ab33775 anti-rat CD4 purified antibody, GAM PE

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

OX-35

アイソタイプ

IgG2a

軽鎖のタイプ

kappa

キャリアフリー

交差種

Rat

アプリケーション

Flow Cyt

applications

免疫原

Cell preparation containing Cd4 protein. The exact immunogen used to generate this antibody is proprietary information.

P05540

エピトープ

This antibody recognises a different epitope on the CD4 molecule than the W3/25 monoclonal (eg ab33779 and ab33783).

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1-4 µg/mL", "FlowCyt-species-notes": "<p></p>" } } }

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下記製品にもご興味をお持ちいただけるかもしれません:

AB234569

Human CD4 ELISA Kit

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こちらの製品も推奨する理由

この製品は、同様の実験や関連する研究で広く使用されていることから推奨させていただいております。

お客様の実験に適するかご確認いただくため、必ず製品データシートをご確認いただくことをお勧めいたします。ご不明点等ございましたら、テクニカルサポートチームまでお問い合わせください。

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein A

精製に関する特記事項

Purified by Protein A affinity chromatography

バッファー組成

pH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.

See full target information Cd4

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文献 (11)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 24: PubMed37175970

2023

Combined Supplementation of and Diminishes Chronic Unpredictable Mild Stress-Induced Intestinal Alterations via Activation of Nrf-2 Signaling Pathway in Rats.

Applications

Unspecified application

Species

Unspecified reactive species

Sabiha Fatima,Haifa Altwaijry,Mahmoud M A Abulmeaty,Manal Abudawood,Nikhat J Siddiqi,Reem Hamoud Alrashoudi,Sarah Alsobaie

iScience 26:106647 PubMed37168574

2023

Intrauterine desensitization enables long term survival of human oligodendrocyte progenitor cells without immunosuppression.

Applications

Unspecified application

Species

Unspecified reactive species

Dou Ye,Suqing Qu,Yinxiang Yang,Zhaoyan Wang,Qian Wang,Weipeng Liu,Fan Zhang,Qian Guan,Xiaohua Wang,Jing Zang,Xin Li,Hengtao Liu,Ruiqin Yao,Zhichun Feng,Zuo Luan

EJNMMI research 12:6 PubMed35107664

2022

Dimethyl fumarate decreases short-term but not long-term inflammation in a focal EAE model of neuroinflammation.

Applications

Unspecified application

Species

Unspecified reactive species

S K Vainio,A M Dickens,M Matilainen,F R López-Picón,R Aarnio,O Eskola,O Solin,D C Anthony,J O Rinne,L Airas,M Haaparanta-Solin

Movement disorders : official journal of the Movement Disorder Society 37:613-619 PubMed34766658

2021

Spontaneous Graft-Induced Dyskinesias Are Independent of 5-HT Neurons and Levodopa Priming in a Model of Parkinson's Disease.

Applications

Unspecified application

Species

Unspecified reactive species

Emma L Lane,David J Harrison,Elena Ramos-Varas,Rachel Hills,Sophie Turner,Mariah J Lelos

Journal of inflammation research 14:2979-2991 PubMed34262323

2021

Overexpression of Neutrophil MMP-9 and HIF-1α May Contribute to the Finger-Like Projections Formation and Histo-Pathogenesis in Nasal Inverted Papilloma.

Applications

Unspecified application

Species

Unspecified reactive species

Tao Li,Kai Sen Tan,Yan Yi Tu,Li Zhao,Jing Liu,Hsiao Hui Ong,De Yun Wang,Li Shi

Experimental neurology 282:78-85 PubMed27235932

2016

hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation.

Applications

IHC

Species

Rat

Andreas Heuer,Agnete Kirkeby,Ulrich Pfisterer,Marie E Jönsson,Malin Parmar

American journal of physiology. Heart and circulat 305:H1761-71 PubMed24097428

2013

Inhibition of NF-κB activation by a novel IKK inhibitor reduces the severity of experimental autoimmune myocarditis via suppression of T-cell activation.

Applications

Unspecified application

Species

Unspecified reactive species

Ryo Watanabe,Ryoko Wakizono Azuma,Jun-ichi Suzuki,Masahito Ogawa,Akiko Itai,Yasunobu Hirata,Issei Komuro,Mitsuaki Isobe

Molecular therapy : the journal of the American So 21:1862-75 PubMed23799534

2013

Dose-dependent neuroprotection of VEGF₁₆₅ in Huntington's disease striatum.

Applications

Unspecified application

Species

Unspecified reactive species

Stuart M Ellison,Antonio Trabalza,Veronica Tisato,Evangelos Pazarentzos,Shirley Lee,Vasiliki Papadaki,Despoina Goniotaki,Sarah Morgan,Nazanin Mirzaei,Nicholas D Mazarakis

Artificial organs 37:600-5 PubMed23452255

2013

Pathological effects of processed bovine pericardial scaffolds--a comparative in vivo evaluation.

Applications

IHC

Species

Rat

Parvathy Thampi,Divakaran Nair,Lalithakunjamma R,Vijayan N,Syam Venugopal,Umashankar Ramachandra

Toxicologic pathology 36:795-804 PubMed18776164

2008

A dual-label technique for the immunohistochemical demonstration of T-lymphocyte subsets in formalin-fixed, paraffin-embedded rat lymphoid tissue.

Applications

Unspecified application

Species

Unspecified reactive species

Kevin J Randall,Gail Pearse

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

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Anti-CD4 抗体 [OX-35]

Anti-CD4 antibody [OX-35]

Flow Cytometry - Anti-CD4 antibody [OX-35] (AB33775)

Flow Cytometry - Anti-CD4 antibody [OX-35] (AB33775)

関連する標識済み抗体及び組成の異なる製品 (1)

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

軽鎖のタイプ

キャリアフリー

交差種

アプリケーション

免疫原

エピトープ

Reactivity data

下記製品にもご興味をお持ちいただけるかもしれません:

Human CD4 ELISA Kit

こちらの製品も推奨する理由

出荷温度及び保存条件

製品の状態

精製方法

精製に関する特記事項

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

製品プロトコール

ターゲットの情報

文献 (11)

Abcam product promise

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