JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB269348

Anti-CD4 抗体 [GK1.5]

Anti-CD4 antibody [GK1.5]

Be the first to review this product! Submit a review

|

(3 Publications)

Rat Monoclonal CD4 antibody. Carrier free. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 3 publications. Immunogen corresponding to Cell preparation containing Cd4 protein.

別名を表示する

CD4, T-cell surface glycoprotein CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, Cd4

3 Images
Flow Cytometry - Anti-CD4 antibody [GK1.5] (AB269348)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-CD4 antibody [GK1.5] (AB269348)

Flow cytometric analysis of mouse splenocyte suspension stained with 4 μg / ml ab269348 where CD4 positive cells are in red and CD4 negative cells are in black.

Flow Cytometry - Anti-CD4 antibody [GK1.5] (AB269348)
  • Flow Cyt

Unknown

Flow Cytometry - Anti-CD4 antibody [GK1.5] (AB269348)

Flow cytometry analysis (surface staining) of CD4 in murine splenocytes labeling CD4 with ab269348.

Flow Cytometry - Anti-CD4 antibody [GK1.5] (AB269348)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-CD4 antibody [GK1.5] (AB269348)

Flow cytometry pattern of mouse splenocyte suspension stained with ab269348 with a concentration of 4 μg / ml in the sample

関連する標識済み抗体及び組成の異なる製品 (7)

  • 660 APC

    APC Anti-CD4 antibody [GK1.5]

  • 519 FITC

    FITC Anti-CD4 antibody [GK1.5]

  • 519 FITC

    FITC Anti-CD4 antibody [GK1.5]

  • 667 PE/Cy5®

    PE/Cy5® Anti-CD4 antibody [GK1.5]

  • 695 PerCP/Cy5.5®

    PerCP/Cy5.5® Anti-CD4 antibody [GK1.5]

  • 704 redFluor™ 710

    redFluor™ 710 Anti-CD4 antibody [GK1.5]

  • 450 violetFluor™ 450

    violetFluor™ 450 Anti-CD4 antibody [GK1.5]

Key facts

宿主種

Rat

クローン性

Monoclonal

クローン番号

GK1.5

アイソタイプ

IgG2b

キャリアフリー

Yes

交差種

Mouse

アプリケーション

Flow Cyt

applications

免疫原

Cell preparation containing Cd4 protein. The exact immunogen used to generate this antibody is proprietary information.

P06332

style
left-column

代替製品

Primary Antibodies

AB183685

Anti-CD4 antibody [EPR19514]

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD4 antibody [EPR19514] (AB183685)

  • 5
  • 21
Primary Antibodies

AB181724

Anti-CD4 antibody [EPR6855] - BSA and Azide free

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD4 antibody [EPR6855] - BSA and Azide free (AB181724)

  • 4
  • 9
Primary Antibodies

AB237722

Anti-CD4 antibody [CAL4]

20ul selling size|BOND RX™ Validated|Recombinant|Lab Essentials|RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD4 antibody [CAL4] (AB237722)

  • 5
  • 1
Primary Antibodies

AB221775

Anti-CD4 antibody [EPR19514] - Low endotoxin, Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD4 antibody [EPR19514] - Low endotoxin, Azide free (AB221775)

  • 0
  • 0
Primary Antibodies

AB213215

Anti-CD4 antibody [SP35]

BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials|Advanced Validation|20ul selling size

Multiplex immunohistochemistry - Anti-CD4 antibody [SP35] (AB213215)

  • 4
  • 3
Primary Antibodies

AB133616

Anti-CD4 antibody [EPR6855]

BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD4 antibody [EPR6855] (AB133616)

  • 5
  • 20
Primary Antibodies

AB277931

Alexa Fluor® 594 Anti-CD4 antibody [EPR6855]

BOND RX™ Validated|RabMAb|Recombinant|Trial Size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 594 Anti-CD4 antibody [EPR6855] (AB277931)

  • 0
  • 0

組合せ製品

Assay Kits

AB234569

Human CD4 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human CD4 ELISA Kit (AB234569)

  • 0
  • 0
Primary Antibodies

AB24982

Cy5 ® Anti-CD45.1 antibody [A20]

  • 0
  • 0
Primary Antibodies

AB237365

Alexa Fluor® 647 Anti-CD8 alpha antibody [EPR21769]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-CD8 alpha antibody [EPR21769] (AB237365)

  • 0
  • 0
Primary Antibodies

AB307134

Alexa Fluor® 488 Anti-CD3 antibody [SP162]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 488 Anti-CD3 antibody [SP162] (AB307134)

  • 0
  • 0
Primary Antibodies

AB303467

Alexa Fluor® 647 Anti-Ly6g antibody [EPR22909-135]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-Ly6g antibody [EPR22909-135] (AB303467)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "10 µL for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }
style
left-column
style
left-column

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein G
バッファー組成
pH: 7.4 Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
style
left-column
style
left-column
style
left-column

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

ターゲットの情報

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.
See full target information Cd4
style
left-column

文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in immunology 16:1581878 PubMed40539039

2025

Identification of the microglia-associated signature in experimental autoimmune encephalomyelitis.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Wu,Jianhong Wang,Bo Chen,Yuxue Guo,Ping Gan,Yanbing Han

Biotechnology journal 20:e202400574 PubMed39989253

2025

Methionine Restriction Exerts Anti-Tumor Immunity via Joint Intervention of T-Bet Palmitoylation in Gastric Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Lin Xin,He-Song Xu,Luo-Jun Fan,Chuan Liu,Yong-Hui Zou,Qi Zhou,Zhen-Qi Yue,Jin-Heng Gan,Jiang Liu

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 44:367-383 PubMed37974301

2023

CCL5 mediated astrocyte-T cell interaction disrupts blood-brain barrier in mice after hemorrhagic stroke.

Applications

Unspecified application

Species

Unspecified reactive species

Shiyi Zhou,Chang Liu,Jixian Wang,Jing Ye,Qianyuan Lian,Lin Gan,Shiyu Deng,Tongtong Xu,Yiyan Guo,Wanlu Li,Zhijun Zhang,Guo-Yuan Yang,Yaohui Tang
View all publications
style
left-column
style
left-column
style
right-column

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com