AB182981

Anti-CD31 抗体 [EPR17259]

Name: Anti-CD31 抗体 [EPR17259] (ab182981) | Abcam
Brand: Abcam Limited
SKU: AB182981
Rating: 5 (22 reviews)

Anti-CD31 antibody [EPR17259]

BOND RX™ Validated
RabMAb
Recombinant
Lab Essentials
20ul selling size
Advanced Validation
詳細を見る

(22 Reviews)

(224 Publications)

Anti-CD31 antibody [EPR17259] (ab182981) is a rabbit monoclonal antibody detecting CD31 in IHC-P, mIHC. Suitable for Human, Mouse, Rat.

- Multiplex IHC validated on the Leica BOND® MAX using Opal reagents
- Biophysical QC for unrivalled batch-batch consistency
- Over 220 publications

別名を表示する

CD31, Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, PECAM1

11 Images

Multiplex immunohistochemistry - Anti-CD31 antibody [EPR17259] (AB182981)

mIHC

Supplier Data

Multiplex immunohistochemistry - Anti-CD31 antibody [EPR17259] (AB182981)

Fluorescence multiplex immunohistochemical analysis of the human endometrium (Formalin/PFA-fixed paraffin-embedded sections). Panel A : merged staining of anti-EpCAM (ab223582, magenta; Opal™690), anti-NKG2A (ab260035, green; Opal™520) and anti-CD31 (ab182981, red; Opal™570) on human endometrium. Panel B : anti-NKG2A stained on NK cells. Panel C : anti-CD31 stained on endothelial cells. Panel D : anti-EpCAM stained on glandular cells. Opal Polymer HRP Ms + Rb was used as a secondary antibody. The section was incubated in three rounds of staining : in the order of ab223582 at 1/500 dilution (1.008 μg/ml), ab260035 at 1/2000 dilution (0.262 μg/ml) and ab182981 at 1/4000 dilution (0.137 μg/ml) for 30 mins at room temperature. Each round was followed by a separate fluorescent tyramide signal amplification system. The immunostaining was performed on a Leica Biosystems BOND® RX instrument with an Opal™ 4-color kit. Image acquisition was performed with Leica SP8 confocal microscope. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0, epitope retrieval solution2) for 20 mins. DAPI (blue) was used as a nuclear counter stain.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

IHC-P

Lab

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemical analysis of formalin fixed paraffin embedded human lung labelling CD31 with ab182981 at a concentration of 0.52 µg/ml. The immunostaining was performed on a Ventana DISCOVERY ULTRA (Roche Tissue Diagnostics) instrument with an OptiView DAB IHC Detection Kit. Heat mediated antigen retrieval was conducted for 32 mins at 100°C with ULTRA cell conditioning solution (CC1, pH 8.5). ab182981Anti-CD31 antibody was incubated at 37°C for 16 mins. Sections were counterstained with Hematoxylin II. Image inset shows absence of staining in secondary antibody only control.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemical analysis of paraffin-embedded human lung tissue labeling CD31 with ab182981 at 1/2000 dilution followed by Goat Anti-Rabbit IgG H&L (HRP) ready to use. Membranous staining on endothelial cells in human lung (PMID : 16234507) is observed. Counterstained with hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) ready to use.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

IHC-P

Lab

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemical analysis of formalin fixed paraffin embedded human lung labelling CD31 with ab182981 at a concentration of 0.35 µg/ml. The immunostaining was performed on a Leica Biosystems BOND^® RX instrument with a Bond™ Polymer Refine Detection kit. Heat mediated antigen retrieval was performed with Tris-EDTA buffer (pH 9.0, Epitope Retrieval Solution 2) for 20 mins.ab182981Anti-CD31 antibody was incubated for 30 mins at room temperature. Sections were counterstained with Hematoxylin. Image inset shows absence of staining in secondary antibody only control.

mIHC

Lab

Multiplex immunohistochemistry - Anti-CD31 antibody [EPR17259] (AB182981)

Multiplex immunohistochemistry analysis of formalin/PFA-fixed paraffin-embedded mouse placenta tissue staining LOX 1 with ab317689 at a 1/2000 dilution, ab324045 anti-AP2 gamma used at 1/500 dilution and ab182981 anti-CD31 used at a 1/5000 dilution.

Panel A : merged staining of anti-LOX 1 (green; Opal™520), anti-AP2 gamma (magenta; Opal™690) and anti-CD31 (gray; Opal™570) on mouse placenta.

Panel B : anti-LOX 1 staining trophoblast in mouse placenta.

Panel C : ant-AP2 gamma staining trophoblast stem cell in mouse placenta.

Panel D : ant-CD31 staining endothelium in mouse placenta.

Nuclear DNA was labeled with DAPI (shown in blue).

The section was incubated in three rounds of staining : in the order of ab317689, ab324045 and ab182981 for 30 mins at room temperature. Each round was followed by a separate fluorescent tyramide signal amplification system.

The immunostaining was performed on a Leica Biosystems BOND® RX instrument with an Opal™ 4-color kit. Image acquisition was performed with Leica SP8 confocal microscope.

Heat mediated antigen retrieval was performed with Tris-EDTA buffer (pH 9.0, Epitope Retrieval Solution 2) for 20 mins.

mIHC

Lab

Multiplex immunohistochemistry - Anti-CD31 antibody [EPR17259] (AB182981)

Panel A : merged staining of anti-LOX 1 (green; Opal™520), anti-AP2 gamma (magenta; Opal™690) and anti-CD31 (gray; Opal™570) on mouse placenta.

Panel B : anti-LOX 1 staining trophoblast in mouse placenta.

Panel C : ant-AP2 gamma staining trophoblast stem cell in mouse placenta.

Panel D : ant-CD31 staining endothelium in mouse placenta.

Nuclear DNA was labeled with DAPI (shown in blue).

The immunostaining was performed on a Leica Biosystems BOND® RX instrument with an Opal™ 4-color kit. Image acquisition was performed with Leica SP8 confocal microscope.

Heat mediated antigen retrieval was performed with Tris-EDTA buffer (pH 9.0, Epitope Retrieval Solution 2) for 20 mins.

mIHC

Lab

Multiplex immunohistochemistry - Anti-CD31 antibody [EPR17259] (AB182981)

Multiplex immunohistochemistry analysis of formalin/PFA-fixed paraffin-embedded mouse liver tissue staining ALDH1L1 with ab307696 at a 1/5000 dilution, ab182981 anti-CD31 used at 1/5000 dilution and ab315474 anti-ABCB11 used at a 1/2000 dilution. Opal Polymer HRP Ms + Rb was used as a secondary antibody.

Panel A : merged staining of anti-ALDH1L1 (green; Opal™520), anti-CD31 (magenta; Opal™690) and anti-ABCB11 (grey; Opal™570) on mouse liver.
Panel B : anti-ALDH1L1 staining hepatocytes in mouse liver.
Panel C : anti-CD31 staining endothelium in mouse liver.
Panel D : anti-ABCB11 staining bile canaliculi in mouse liver.
Nuclear DNA was labeled with DAPI (shown in blue).

The section was incubated in three rounds of staining : in the order of ab307696, ab182981 and ab315474 for 30 mins at room temperature. Each round was followed by a separate fluorescent tyramide signal amplification system.

Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0, epitope retrieval solution2) for 20 mins.

mIHC

Lab

Multiplex immunohistochemistry - Anti-CD31 antibody [EPR17259] (AB182981)

Multiplex immunohistochemistry analysis of formalin/PFA-fixed paraffin-embedded rat liver tissue staining ALDH1L1 with ab307696 at a 1/5000 dilution, ab182981 anti-CD31 used at 1/5000 dilution and ab315474 anti-ABCB11 used at a 1/2000 dilution. Opal Polymer HRP Ms + Rb was used as a secondary antibody.

Panel A : merged staining of anti-ALDH1L1 (green; Opal™520), anti-CD31 (magenta; Opal™690) and anti-ABCB11 (grey; Opal™570) on mouse liver.
Panel B : anti-ALDH1L1 staining hepatocytes in rat liver.
Panel C : anti-CD31 staining endothelium in rat liver.
Panel D : anti-ABCB11 staining bile canaliculi in rat liver.
Nuclear DNA was labeled with DAPI (shown in blue).

Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0, epitope retrieval solution2) for 20 mins.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemical analysis of paraffin-embedded human kidney tissue labeling CD31 with ab182981 at 1/2000 dilution followed by Goat Anti-Rabbit IgG H&L (HRP) ready to use. Membranous staining on endothelial cells in human kidney (PMID : 16234507) is observed. Counterstained with hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) ready to use.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemical analysis of paraffin-embedded rat lung tissue labeling CD31 with ab182981 at 1/2000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) ready to use. Membranous staining on endothelial cells in rat lung (PMID : 16234507) is observed. Counterstained with hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) ready to use.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemical analysis of paraffin-embedded mouse lung tissue labeling CD31 with ab182981 at 1/2000 dilution followed by Goat Anti-Rabbit IgG H&L (HRP) ready to use. Membranous staining on endothelial cells in mouse lung (PMID : 16234507) is observed. Counterstained with hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) ready to use.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR17259

アイソタイプ

IgG

キャリアフリー

交差種

Mouse, Rat, Human

アプリケーション

IHC-P, mIHC

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "mIHC" : {"fullname" : "Multiplex immunohistochemistry", "shortname":"mIHC"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "mIHC-species-checked": "testedAndGuaranteed", "mIHC-species-dilution-info": "1/4000", "mIHC-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/2000", "IHCP-species-notes": "In our hands we observed non-specific cytoplasmic staining on tubular cells in rat kidney.The ideal fixation time will depend on the size of the tissue block and the type of tissue, but fixation between 18–24h is suitable for most samples.Positive Control: human lung tissue. Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." }, "Mouse": { "mIHC-species-checked": "testedAndGuaranteed", "mIHC-species-dilution-info": "1/5000", "mIHC-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/2000", "IHCP-species-notes": "In our hands we observed non-specific cytoplasmic staining on tubular cells in rat kidney.The ideal fixation time will depend on the size of the tissue block and the type of tissue, but fixation between 18–24h is suitable for most samples.Positive Control: human lung tissue. Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." }, "Rat": { "mIHC-species-checked": "testedAndGuaranteed", "mIHC-species-dilution-info": "1/5000", "mIHC-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/2000", "IHCP-species-notes": "In our hands we observed non-specific cytoplasmic staining on tubular cells in rat kidney.The ideal fixation time will depend on the size of the tissue block and the type of tissue, but fixation between 18–24h is suitable for most samples.Positive Control: human lung tissue. Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." } } }

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下記製品にもご興味をお持ちいただけるかもしれません:

AB190814

Human CD31 ELISA Kit (PECAM)

0 Reviews

製品ページを見る

こちらの製品も推奨する理由

この製品は、同様の実験や関連する研究で広く使用されていることから推奨させていただいております。

お客様の実験に適するかご確認いただくため、必ず製品データシートをご確認いただくことをお勧めいたします。ご不明点等ございましたら、テクニカルサポートチームまでお問い合わせください。

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製品の詳細

Anti-CD31 antibody [EPR17259] (ab182981) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in IHC-P and mIHC.

Anti-CD31 antibody [EPR17259] (ab182981) was first used in a scientific publication in 2018 and has been cited over 224 times in peer reviewed journals. It's performance in IHC in human, mouse and rat samples is trusted by the scientific community.

Abcam's high quality manufacturing and validation processes ensure Anti-CD31 antibody [EPR17259] (ab182981) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.

Anti-CD31 antibody [EPR17259] (ab182981) has 19 independent reviews from customers.

Anti-CD31 antibody [EPR17259] (ab182981) specifically detects CD31 (UniProt ID: Q08481; Molecular weight: 80kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL).

Conjugation-ready, carrier free format available for antibody clone EPR17259 - ab225883.

Antibody clone EPR17259 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor^® 647, Alexa Fluor^® 488, Alexa Fluor^® 555 (ab305210, ab305267, ab312892).

CD31 (PECAM-1) is a protein expressed on endothelial and immune cells, playing a crucial role in tumor angiogenesis and immune cell trafficking. In immuno-oncology, it influences the tumor microenvironment and modulates the immune response to cancer.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein A

バッファー組成

pH: 7.2 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

CD31 also known as Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) is a protein with a mass of approximately 130 kDa. This protein is an important component of the cell surface and is expressed mainly in endothelial cells and certain leukocyte populations. It plays a role in cell-cell adhesion and is recognized as an important marker in immunohistochemistry (IHC) for identifying endothelial cells. CD31 is valuable for researchers focusing on vascular biology and immunology serving as a beacon for cells involved in forming blood vessels or those located within the vascular system.

Biological function summary

CD31 is important for the transendothelial migration of leukocytes. It forms complex interactions with itself (homophilic binding) and other partners to mediate processes necessary for immune response and tissue integrity. This protein supports the development and maintenance of endothelial cell junctions making it fundamental in maintaining vascular permeability. Additionally CD31 plays a role in transmitting signals that influence the survival of leukocytes and endothelial cells. Its expression and function help regulate the balance between cell life and death impacting immune function and tissue repair.

Pathways

CD31 participates actively in both immune and angiogenesis pathways. It associates with proteins like SHP-2 and SHP-1 which are involved in downstream signaling cascades critical for cell signaling and immune cell activation. Within the angiogenesis pathway CD31 interacts with other adhesion molecules to promote new blood vessel formation under physiological and pathological conditions. It also collaborates with integrins influencing cellular responses to external stimuli and contributing to vascular remodeling and repair.

CD31 is significantly associated with inflammatory conditions and cardiovascular diseases. For instance its dysfunction or altered expression can contribute to atherosclerosis a disease characterized by the hardening of arteries due to plaque buildup. Furthermore CD31 deficiencies have links with autoimmune disorders where it might affect leukocyte migration and contribute to tissue damage. The protein associates with ICAM-1 during inflammatory processes illustrating its complex involvement in disease progression and potential as a therapeutic target.

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed : 17580308, PubMed : 19342684). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed : 19342684). Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions (PubMed : 27958302). Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (PubMed : 17580308). Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (PubMed : 12110892). Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes (PubMed : 12110892). Modulates bradykinin receptor BDKRB2 activation (PubMed : 18672896). Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells (PubMed : 18672896). Induces susceptibility to atherosclerosis (By similarity).. Isoform Delta15. Does not protect against apoptosis.

See full target information PECAM1

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文献 (224)

Recent publications for all applications. Explore the full list and refine your search

Investigative ophthalmology & visual science 64:34 PubMed38010699

2023

Nicotinamide Prevents Retinal Vascular Dropout in a Rat Model of Ocular Hypertension and Supports Ocular Blood Supply in Glaucoma Patients.

Applications

Unspecified application

Species

Unspecified reactive species

Simon T Gustavsson,Tim J Enz,James R Tribble,Mattias Nilsson,Anna Lindqvist,Christina Lindén,Anna Hagström,Carola Rutigliani,Emma Lardner,Gustav Stålhammar,Pete A Williams,Gauti Jóhannesson

Cancers 15: PubMed38001741

2023

Mobilization of Circulating Tumor Cells after Short- and Long-Term FOLFIRINOX and GEM/nab-PTX Chemotherapy in Xenograft Mouse Models of Human Pancreatic Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yukako Ito,Shinji Kobuchi,Amiri Kawakita,Kazuki Tosaka,Yume Matsunaga,Shoma Yoshioka,Shizuka Jonan,Kikuko Amagase,Katsunori Hashimoto,Mitsuro Kanda,Takuya Saito,Hayao Nakanishi

Cell death & disease 14:756 PubMed37980402

2023

Inhibition of PDGFRβ alleviates endothelial cell apoptotic injury caused by DRP-1 overexpression and mitochondria fusion failure after mitophagy.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaohong An,Xiao Ma,Heng Liu,Jing Song,Tiange Wei,Rongzhan Zhang,Xiao Zhan,Hongyang Li,Jia Zhou

Journal of translational medicine 21:817 PubMed37974228

2023

HOXD9/miR-451a/PSMB8 axis is implicated in the regulation of cell proliferation and metastasis via PI3K/AKT signaling pathway in human anaplastic thyroid carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yong Zhong,Fan Yu,Ling Yang,Yu Wang,Lin Liu,Chengyou Jia,Haidong Cai,Jianshe Yang,Shiyang Sheng,Zhongwei Lv,Li Weng,Bo Wu,Xiaoping Zhang

Journal of neuroinflammation 20:251 PubMed37915090

2023

The novel HS-mimetic, Tet-29, regulates immune cell trafficking across barriers of the CNS during inflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Tessa Peck,Connor Davis,Georgia Lenihan-Geels,Maddie Griffiths,Sam Spijkers-Shaw,Olga V Zubkova,Anne Camille La Flamme

Infection and drug resistance 16:6807-6820 PubMed37904831

2023

Experimental Research on the Effect of Tounong San on the Immune Function of Rats with Superficial Suppurative Infection.

Applications

Unspecified application

Species

Unspecified reactive species

Zhiqiang Shi,Yu Liu,Xiaodan Chang,Yuan Gao,Min Hao,Shuo Feng,Haoyu Dong

International endodontic journal 57:37-49 PubMed37874659

2023

Sensory nerves, but not sympathetic nerves, promote reparative dentine formation after dentine injury via CGRP-mediated angiogenesis: An in vivo study.

Applications

Unspecified application

Species

Unspecified reactive species

Chaoning Zhan,Minchun Huang,Junyang Chen,Yanli Lu,Xiaojun Yang,Jin Hou

NPJ Regenerative medicine 8:59 PubMed37857652

2023

Repair of osteochondral defects: efficacy of a tissue-engineered hybrid implant containing both human MSC and human iPSC-cartilaginous particles.

Applications

Unspecified application

Species

Unspecified reactive species

Shinichi Nakagawa,Wataru Ando,Kazunori Shimomura,David A Hart,Hiroto Hanai,George Jacob,Ryota Chijimatsu,Seido Yarimitu,Hiromichi Fujie,Seiji Okada,Noriyuki Tsumaki,Norimasa Nakamura

Cells 12: PubMed37887332

2023

Inducing Angiogenesis in the Nucleus Pulposus.

Applications

Unspecified application

Species

Unspecified reactive species

Sheela R Damle,Agata K Krzyzanowska,Maximilian K Korsun,Kyle W Morse,Susannah Gilbert,Han Jo Kim,Oheneba Boachie-Adjei,Bernard A Rawlins,Marjolein C H van der Meulen,Matthew B Greenblatt,Chisa Hidaka,Matthew E Cunningham

Journal of translational medicine 21:732 PubMed37848931

2023

The HIFIA/LINC02913/IGF1R axis promotes the cell function of adipose-derived mesenchymal stem cells under hypoxia via activating the PI3K/AKT pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Xiang Xiong,Liqin Yuan,Kai Yang,Xiancheng Wang

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

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Anti-CD31 抗体 [EPR17259]

Anti-CD31 antibody [EPR17259]

Multiplex immunohistochemistry - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

Multiplex immunohistochemistry - Anti-CD31 antibody [EPR17259] (AB182981)

Multiplex immunohistochemistry - Anti-CD31 antibody [EPR17259] (AB182981)

Multiplex immunohistochemistry - Anti-CD31 antibody [EPR17259] (AB182981)

Multiplex immunohistochemistry - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [EPR17259] (AB182981)

関連する標識済み抗体及び組成の異なる製品 (4)

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

Reactivity data

下記製品にもご興味をお持ちいただけるかもしれません:

Human CD31 ELISA Kit (PECAM)

こちらの製品も推奨する理由

製品の詳細

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (224)

Abcam product promise

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