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AB46922

Anti-CD31 抗体 [B-B38] - BSA and Azide free

Anti-CD31 antibody [B-B38] - BSA and Azide free

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(1 Publication)

Mouse Monoclonal CD31 antibody. Carrier free. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human PECAM1.

別名を表示する

CD31, Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, PECAM1

1 Images
Flow Cytometry - Anti-CD31 antibody [B-B38] - BSA and Azide free (AB46922)
  • Flow Cyt

Unknown

Flow Cytometry - Anti-CD31 antibody [B-B38] - BSA and Azide free (AB46922)

Flow cytometry analysis staining CD31 in human platelet cells using ab27333.

This image was generated using the ascites version of the product.

This data was developed using the same antibody clone in a different buffer formulation.

関連する標識済み抗体及び組成の異なる製品 (1)

  • 519 FITC

    FITC Anti-CD31 antibody [B-B38]

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

B-B38

アイソタイプ

IgG1

軽鎖のタイプ

kappa

キャリアフリー

Yes

交差種

Human

アプリケーション

Flow Cyt

applications

免疫原

Recombinant Full Length Protein corresponding to Human PECAM1.

P16284

特異性

This antibody is specific for CD31. Recognizes the soluble antigen

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p><a href='/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Ion exchange chromatography
精製に関する特記事項
Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free.
バッファー組成
pH: 7.3 - 7.5 Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
+4°C|-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed : 17580308, PubMed : 19342684). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed : 19342684). Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions (PubMed : 27958302). Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (PubMed : 17580308). Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (PubMed : 12110892). Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes (PubMed : 12110892). Modulates bradykinin receptor BDKRB2 activation (PubMed : 18672896). Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells (PubMed : 18672896). Induces susceptibility to atherosclerosis (By similarity).. Isoform Delta15. Does not protect against apoptosis.
See full target information PECAM1

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular medicine 37:359-68 PubMed26707630

2015

Asymmetric stem-cell division ensures sustained keratinocyte hyperproliferation in psoriatic skin lesions.

Applications

Unspecified application

Species

Unspecified reactive species

Hai-Yan Jia,Ying Shi,Long-Fei Luo,Guan Jiang,Qiong Zhou,Shi-Zheng Xu,Tie-Chi Lei
View all publications

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