Anti-CD21 抗体 [B-E5] - BSA and Azide free (ab46900)
![Flow Cytometry - Anti-CD21 antibody [B-E5] (ab46900)](https://www.abcam.co.jp/ps/products/46/ab46900/Images/ab46900.gif "Flow Cytometry - Anti-CD21 antibody [B-E5] (ab46900)")
Key features and details
- Mouse monoclonal [B-E5] to CD21 - BSA and Azide free
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG2a
製品の概要
-
製品名
Anti-CD21 antibody [B-E5] - BSA and Azide free
CD21 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [B-E5] to CD21 - BSA and Azide free -
由来種
Mouse -
特異性
Recognises the Epstein-Barr virus receptor (EBV R), CR2, C3d R, a 110 kDa protein.
Induces human B-cell proliferation and competes with EBV for CD21 binding.
-
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human CD21. Daudi cell line
-
ポジティブ･コントロール
- human lymphocytes
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Constituent: 100% PBS
Sterile-filtered through 0.22 µm. Carrier and preservative free -
キャリア・フリー
はい -
Concentration information loading... -
精製度
Ion Exchange Chromatography -
特記事項（精製）
Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free. -
ポリ/モノ
モノクローナル -
クローン名
B-E5 -
ミエローマ
x63-Ag8.653 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab46900の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
ターゲット情報
-
機能
Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. -
組織特異性
Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen. -
関連疾患
Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. -
配列類似性
Belongs to the receptors of complement activation (RCA) family.
Contains 15 Sushi (CCP/SCR) domains. -
細胞内局在
Membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 1380 Human
- Omim: 120650 Human
- SwissProt: P20023 Human
- Unigene: 445757 Human
-
別名
- C3DR antibody
- CD 21 antibody
- CD21 antibody
see all
画像
-
Flow Cytometry - Anti-CD21 antibody [B-E5] (ab46900)A typical lymphocytes staining pattern with ab46900.
データシートおよび資料
-
Datasheet download
参考文献 (0)
ab46900 は論文での使用が確認できていません。
