Anti-CD19 抗体 [HIB19] - Low endotoxin, Azide free (ab185768)
Key features and details
- Mouse monoclonal [HIB19] to CD19 - Low endotoxin, Azide free
- Suitable for: Flow Cyt, Functional Studies
- Reacts with: Human
- Isotype: IgG1
Related conjugates and formulations
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-CD19 antibody [HIB19] - Low endotoxin, Azide free
CD19 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [HIB19] to CD19 - Low endotoxin, Azide free -
由来種
Mouse -
アプリケーション
適用あり: Flow Cyt, Functional Studiesmore details -
種交差性
交差種: Human -
免疫原
The details of the immunogen for this antibody are not available.
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ポジティブ･コントロール
- Normal Human peripheral blood cells
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特記事項
Endotoxin Level: Less than 0.001 ng/ug antibody, as determined by the LAL assay.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Aqueous buffer -
キャリア・フリー
はい -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
Functional grade purified. -
ポリ/モノ
モノクローナル -
クローン名
HIB19 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Isotype control
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab185768の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
in a final volume of 100 uL. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
| Functional Studies |
Use at an assay dependent concentration.
|
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. in a final volume of 100 uL. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
Functional Studies
Use at an assay dependent concentration. |
ターゲット情報
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機能
Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. -
関連疾患
Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) [MIM:613493]; also called antibody deficiency due to CD19 defect. CVID3 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. -
配列類似性
Contains 2 Ig-like C2-type (immunoglobulin-like) domains. -
翻訳後修飾
Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 930 Human
- Omim: 107265 Human
- SwissProt: P15391 Human
- Unigene: 652262 Human
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別名
- Antibody deficiency due to defect in CD19 antibody
- Antibody deficiency due to defect in CD19, included antibody
- AW495831 antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (0)
ab185768 は論文での使用が確認できていません。
