Anti-CD11a 抗体 [I21/7] (ab25383)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rat monoclonal [I21/7] to CD11a
- Suitable for: Flow Cyt
- Reacts with: Mouse
Related conjugates and formulations
製品の概要
-
製品名
Anti-CD11a antibody [I21/7]
CD11a 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [I21/7] to CD11a -
由来種
Rat -
アプリケーション
適用あり: Flow Cytmore details
適用なし: IP -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus. This information is proprietary to Abcam and/or its suppliers.
-
ポジティブ・コントロール
- Flow Cyt: Mouse splenocytes.
-
特記事項
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: PBS, 0.05% BSA, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
精製度
Ion Exchange Chromatography -
ポリ/モノ
モノクローナル -
クローン名
I21/7 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
-
Alternative Versions
-
Compatible Secondaries
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab25383の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use a concentration of 0.963 µg/ml.
|
特記事項 |
---|
Flow Cyt
Use a concentration of 0.963 µg/ml. |
ターゲット情報
-
機能
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. -
組織特異性
Leukocytes. -
配列類似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
ドメイン
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
細胞内局在
Membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 16408 Mouse
- SwissProt: P24063 Mouse
- Unigene: 1618 Mouse
-
別名
- Lymphocyte function associated antigen, type 1, alpha subunit antibody
- Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
- Antigen CD11A antibody
see all
画像
-
Flow cytometric analysis of mouse splenocyte cells labelling CD11a with ab25383 at 0.963µg/ml (Right panel) compared with a rat monoclonal IgG isotype(Left panel). Goat F(ab)2 Anti-Rat IgG Fc (Alexa Fluor® 488, ab150161) at 1/2000 dilution was used as the secondary antibody. Gated on viable cells.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab25383 は 1 報の論文で使用されています。
- Trowbridge IS & Omary MB Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1. J Exp Med 154:1517-24 (1981). PubMed: 7299345