Anti-CD105 抗体 [SN6] (ab11414)
Key features and details
- Mouse monoclonal [SN6] to CD105
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
Anti-CD105 antibody [SN6]
CD105 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [SN6] to CD105 -
由来種
Mouse -
特異性
ab11414 recognises the human CD105 cell surface antigen. -
アプリケーション
適用あり: Flow Cytmore details
適用なし: WB -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human CD105.
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ポジティブ・コントロール
- Flow Cyt: KG1 cells.
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特記事項
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
Purified IgG prepared by affinity chromatography. -
ポリ/モノ
モノクローナル -
クローン名
SN6 -
ミエローマ
P3-NS1/1-Ag4-1 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab11414の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
Use 10ul of the neat dilution to label 106 cells in 100ul.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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特記事項 |
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Flow Cyt
Use at an assay dependent concentration. Use 10ul of the neat dilution to label 106 cells in 100ul.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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ターゲット情報
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機能
Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. -
組織特異性
Endoglin is restricted to endothelial cells in all tissues except bone marrow. -
関連疾患
Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 2022 Human
- Omim: 131195 Human
- SwissProt: P17813 Human
- Unigene: 76753 Human
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別名
- AI528660 antibody
- AI662476 antibody
- CD 105 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (71)
ab11414 は 71 報の論文で使用されています。
- Luo B et al. Residual periodontal ligament in the extraction socket promotes the dentin regeneration potential of DPSCs in the rabbit jaw. Stem Cell Res Ther 14:47 (2023). PubMed: 36941706
- Zhang Y et al. Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells. Commun Biol 6:476 (2023). PubMed: 37127734
- Park C et al. Self-assembled adipose-derived mesenchymal stem cells as an extracellular matrix component- and growth factor-enriched filler. Front Cell Dev Biol 11:1219739 (2023). PubMed: 37799276
- Zhang C et al. MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1. Int J Oral Sci 15:48 (2023). PubMed: 37852994
- Perez JE et al. Modulated nanowire scaffold for highly efficient differentiation of mesenchymal stem cells. J Nanobiotechnology 20:282 (2022). PubMed: 35710420