Anti-Cathelicidin/CLP 抗体 [mAbcam 58387] (ab58387)
![Western blot - Anti-Cathelicidin/CLP antibody [mAbcam 58387] (ab58387)](https://www.abcam.co.jp/ps/products/58/ab58387/Images/ab58387-72275-anti-cathelicidin-antibody-mabcam-58387-western-blot.jpg "Western blot - Anti-Cathelicidin/CLP antibody [mAbcam 58387] (ab58387)")
Key features and details
- Mouse monoclonal [mAbcam 58387] to Cathelicidin/CLP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Cathelicidin/CLP antibody [mAbcam 58387]
Cathelicidin/CLP 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [mAbcam 58387] to Cathelicidin/CLP -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Chimpanzee, Gorilla, Orangutan
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免疫原
Synthetic peptide corresponding to Human Cathelicidin/CLP aa 150 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin.
(Peptide available asab106671) -
ポジティブ･コントロール
- This antibody gave a positive signal in human spleen tissue lysate.
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特記事項
CAP18 is the only human cathelicidin found so far and closely resembles CRAMP, the sole member of this gene family in mice. LL-37 is the 37 amino acid C-terminal antibacterial protein.
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
精製度
Protein G purified -
一次抗体 備考
CAP18 is the only human cathelicidin found so far and closely resembles CRAMP, the sole member of this gene family in mice. LL-37 is the 37 amino acid C-terminal antibacterial protein. -
ポリ/モノ
モノクローナル -
クローン名
mAbcam 58387 -
ミエローマ
Sp2/0-Ag14 -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab58387の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 10 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).
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| 特記事項 |
|---|
|
WB
Use a concentration of 10 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa). |
ターゲット情報
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機能
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. -
組織特異性
Expressed in bone marrow and testis and neutrophils. -
配列類似性
Belongs to the cathelicidin family. -
翻訳後修飾
The N-terminus is blocked. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 741881 Chimpanzee
- Entrez Gene: 820 Human
- Omim: 600474 Human
- SwissProt: Q1KLX1 Chimpanzee
- SwissProt: Q1KLY3 Gorilla
- SwissProt: P49913 Human
- SwissProt: Q1KLX2 Orangutan
- Unigene: 51120 Human
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別名
- 18 kDa cationic antimicrobial protein antibody
- Antibacterial peptide LL-37 antibody
- Antibacterial protein FALL-39 antibody
see all
画像
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Western blot - Anti-Cathelicidin/CLP antibody [mAbcam 58387] (ab58387)Anti-Cathelicidin/CLP antibody [mAbcam 58387] (ab58387) at 10 µg/ml + Human spleen tissue lysate - total protein (ab29699) at 20 µg
Secondary
Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 19 kDa
Observed band size: 19 kDa
Additional bands at: 60 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 30 seconds
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab58387 は 2 報の論文で使用されています。
- Zhang X et al. Salivary Protein Panel to Diagnose Systolic Heart Failure. Biomolecules 9:N/A (2019). PubMed: 31766659
- Zhang X et al. Identification and Validation of a Salivary Protein Panel to Detect Heart Failure Early. Theranostics 7:4350-4358 (2017). PubMed: 29158831