AB2012

Anti-Caspase-10/CASP-10 抗体

Name: Anti-Caspase-10/CASP-10 抗体 (ab2012) | Abcam
Brand: Abcam Limited
SKU: AB2012
Price: 75000 JPY
Availability: InStock
Rating: 5 (1 reviews)

Anti-Caspase-10/CASP-10 antibody

(1 Review)

(4 Publications)

Rabbit Polyclonal Caspase-10/CASP-10 antibody. Suitable for ICC, WB and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human CASP10 aa 500 to C-terminus.

別名を表示する

MCH4, CASP10, Caspase-10, CASP-10, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, ICE-like apoptotic protease 4, FLICE2

2 Images

Supplier Data

Immunocytochemistry - Anti-Caspase-10/CASP-10 antibody (AB2012)

Immunocytochemistry/Immunofluorescence of HeLa cells labeling Caspase-10/CASP-10 with Anti-Caspase-10/CASP-10 antibody (ab2012) at 5μg/ml.

Unknown

Western blot - Anti-Caspase-10/CASP-10 antibody (AB2012)

All lanes:

Western blot - Anti-Caspase-10/CASP-10 antibody (ab2012) at 1/1000 dilution

Lane 1:

HeLa whole cell lysate

Lane 2:

Jurkat whole cell lysate

Lane 3:

A431 whole cell lysate

Lane 4:

K562 whole cell lysate

Lane 5:

NIH3T3 whole cell lysate

Predicted band size: 58 kDa

Observed band size: 59 kDa

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Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Human

アプリケーション

WB, ICC

applications

免疫原

Synthetic Peptide within Human CASP10 aa 500 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q92851

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICC-species-checked": "testedAndGuaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Ion exchange chromatography DEAE-C

バッファー組成

pH: 7.2 Preservative: 0.02% Sodium azide

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates effector caspases CASP3, CASP4, CASP6, CASP7, CASP8 and CASP9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.. Isoform 7 can enhance NF-kappaB activity but promotes only slight apoptosis.. Isoform C is proteolytically inactive.

See full target information CASP10

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文献 (4)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular medicine 56: PubMed40937577

2025

CDC5L binds to ELAVL1 to inhibit pyroptosis in hepatocellular carcinoma through the Caspase 3/GSDME signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Shuai Liang,Zhongcheng Zhu,Yangshuo Tang,Shuhua Zhou,Moyan Xiao,Xuejun Gong,Ke Ye

Renal failure 33:192-206 PubMed21332342

2011

Multiple caspases mediate acute renal cell apoptosis induced by bacterial cell wall components.

Applications

Unspecified application

Species

Unspecified reactive species

Marlyn P Langford,David J McGee,Kathy H Ta,Thomas B Redens,Donald E Texada

Clinical cancer research : an official journal of the American Association for Cancer Research 15:1199-209 PubMed19228726

2009

The combined therapeutic effects of bortezomib and fenretinide on neuroblastoma cells involve endoplasmic reticulum stress response.

Applications

Species

Human

Gabriella Pagnan,Daniela Di Paolo,Roberta Carosio,Fabio Pastorino,Danilo Marimpietri,Chiara Brignole,Annalisa Pezzolo,Monica Loi,Luis J V Galietta,Federica Piccardi,Michele Cilli,Beatrice Nico,Domenico Ribatti,Vito Pistoia,Mirco Ponzoni

The Journal of biological chemistry 279:25149-56 PubMed15069074

2004

Caspase-mediated Cleavage of Insulin Receptor Substrate.

Applications

Unspecified application

Species

Unspecified reactive species

Kirsty A Green,Matthew J Naylor,Emma T Lowe,Pengbo Wang,Emma Marshman,Charles H Streuli

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Caspase-10/CASP-10 抗体

Anti-Caspase-10/CASP-10 antibody

Immunocytochemistry - Anti-Caspase-10/CASP-10 antibody (AB2012)

Western blot - Anti-Caspase-10/CASP-10 antibody (AB2012)

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (4)

代替製品

Primary Antibodies

組合せ製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Abcam product promise