Anti-Casein Kinase 1 delta/CSNK1D 抗体 (ab151793)
Key features and details
- Rabbit polyclonal to Casein Kinase 1 delta/CSNK1D
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-Casein Kinase 1 delta/CSNK1D antibody
Casein Kinase 1 delta/CSNK1D 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Casein Kinase 1 delta/CSNK1D -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-P, ICC/IFmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Rat, Cow
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免疫原
Recombinant fragment corresponding to Human Casein Kinase 1 delta/CSNK1D aa 144-361.
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ポジティブ･コントロール
- HeLa and BCL-1 whole cell lysates; HeLa cells; Human hepatoma tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab151793の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 47 kDa.
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| IHC-P |
1/100 - 1/1000.
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| ICC/IF |
1/100 - 1/1000.
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| 特記事項 |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 47 kDa. |
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IHC-P
1/100 - 1/1000. |
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ICC/IF
1/100 - 1/1000. |
ターゲット情報
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機能
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. -
組織特異性
Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. In blood, highly expressed in hemopoietic cells and mature granulocytes. Also found in monocytes and lymphocytes. -
関連疾患
Defects in CSNK1D are a cause of familial advanced sleep-phase syndrome (FASPS) [MIM:604348]. FASPS is characterized by very early sleep onset and offset. Individuals are 'morning larks' with a 4 hours advance of the sleep, temperature and melatonin rhythms. -
配列類似性
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Contains 1 protein kinase domain. -
翻訳後修飾
Autophosphorylated on serine and threonine residues. -
細胞内局在
Cytoplasm. Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 407122 Cow
- Entrez Gene: 1453 Human
- Entrez Gene: 104318 Mouse
- Entrez Gene: 64462 Rat
- Omim: 600864 Human
- SwissProt: P35508 Cow
- SwissProt: P48730 Human
- SwissProt: Q9DC28 Mouse
see all -
別名
- Casein Kinase 1 delta antibody
- Casein kinase I delta isoform antibody
- Casein kinase I isoform delta antibody
see all
画像
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Western blot - Anti-Casein Kinase 1 delta/CSNK1D antibody (ab151793)Anti-Casein Kinase 1 delta/CSNK1D antibody (ab151793) at 1/2000 dilution + BCL-1 whole cell lysate at 30 µg
Predicted band size: 47 kDa
10% SDS PAGE -
Western blot - Anti-Casein Kinase 1 delta/CSNK1D antibody (ab151793)Anti-Casein Kinase 1 delta/CSNK1D antibody (ab151793) at 1/2000 dilution + HeLa cell lysate at 30 µg
Predicted band size: 47 kDa
10% SDS PAGE -
Immunocytochemistry/ Immunofluorescence - Anti-Casein Kinase 1 delta/CSNK1D antibody (ab151793)Confocal immunofluorescence analysis of paraformaldehyde-fixed HeLa cells, labeling Casein Kinase 1 delta/CSNK1D with ab151793 at 1/500 dilution (green). Alpha-tubulin filaments were also labeled (Red).
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Casein Kinase 1 delta/CSNK1D antibody (ab151793)Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue, labeling Casein Kinase 1 delta/CSNK1D with ab151793 at 1/500 dilution.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab151793 は論文での使用が確認できていません。