AB58546

Anti-Cardiac Troponin I (phospho T143) 抗体

Name: Anti-Cardiac Troponin I (phospho T143) 抗体 (ab58546) | Abcam
Brand: Abcam Limited
SKU: AB58546
Price: 78000 JPY
Availability: InStock
Rating: 3 (2 reviews)

Anti-Cardiac Troponin I (phospho T143) antibody

(2 Reviews)

(10 Publications)

Rabbit Polyclonal Cardiac Troponin I phospho T143 antibody. Suitable for ELISA, WB and reacts with Mouse, Rat, Pig, Human samples. Cited in 10 publications. Immunogen corresponding to Synthetic Peptide within Human TNNI3 pT143 aa 100-200.

別名を表示する

TNNC1, TNNI3, Cardiac troponin I

1 Images

Unknown

Western blot - Anti-Cardiac Troponin I (phospho T143) antibody (AB58546)

All lanes:

Western blot - Anti-Cardiac Troponin I (phospho T143) antibody (ab58546) at 1/500 dilution

Lane 1:

Mouse heart extract without immunizing peptide

Lane 2:

Mouse heart extract with immunizing peptide

Predicted band size: 24 kDa

Observed band size: 30 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Mouse, Human, Pig, Rat

アプリケーション

WB, ELISA

applications

免疫原

Synthetic Peptide within Human TNNI3 pT143 aa 100-200. The exact immunogen used to generate this antibody is proprietary information.

P19429

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Mouse": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "" }, "Rat": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Immunogen

精製に関する特記事項

Affinity purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site.

バッファー組成

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride

出荷温度

Blue Ice

短期保存温度

+4°C

長期保存温度

-20°C

保管に関する情報

Stable for 12 months at -20°C

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

See full target information TNNI3 pT143

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文献 (10)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 25: PubMed38474037

2024

Protein Kinase D Plays a Crucial Role in Maintaining Cardiac Homeostasis by Regulating Post-Translational Modifications of Myofilament Proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Melissa Herwig,Merima Begovic,Heidi Budde,Simin Delalat,Saltanat Zhazykbayeva,Marcel Sieme,Luca Schneider,Kornelia Jaquet,Andreas Mügge,Ibrahim Akin,Ibrahim El-Battrawy,Jens Fielitz,Nazha Hamdani

Frontiers in pharmacology 13:1037151 PubMed36483733

2022

Ciprofol attenuates the isoproterenol-induced oxidative damage, inflammatory response and cardiomyocyte apoptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Yunzhao Yang,Zhongyuan Xia,Cheng Xu,Chunchun Zhai,Xi Yu,Siqi Li

Experimental physiology 106:2235-2247 PubMed34605091

2021

Increased myofilament calcium sensitivity is associated with decreased cardiac troponin I phosphorylation in the diabetic rat heart.

Applications

Unspecified application

Species

Unspecified reactive species

Angela C Greenman,Gary M Diffee,Amelia S Power,Gerard T Wilkins,Olivia M S Gold,Jeffrey R Erickson,James C Baldi

Pathobiology : journal of immunopathology, molecul 86:274-284 PubMed31574524

2019

R5 HIV-1 gp120 Activates p38 MAPK to Induce Rat Cardiomyocyte Injury by the CCR5 Coreceptor.

Applications

Unspecified application

Species

Unspecified reactive species

Rui Gao,Qiujuan Fang,Xi Zhang,Qin Xu,Hanhui Ye,Wenyan Guo,Jiao He,Yahong Chen,Ruixing Wang,Zhijuan Wu,Jing Yu

The Journal of general physiology 151:1070-1080 PubMed31366607

2019

Cardiac contractile dysfunction and protein kinase C-mediated myofilament phosphorylation in disease and aging.

Applications

Unspecified application

Species

Unspecified reactive species

Vani S Ravichandran,Himanshu J Patel,Francis D Pagani,Margaret V Westfall

American journal of physiology. Heart and circulat 315:H348-H356 PubMed29775410

2018

Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition.

Applications

Unspecified application

Species

Unspecified reactive species

Victoria N Parikh,Jing Liu,Ching Shang,Christopher Woods,Alex C Chang,Mingming Zhao,David N Charo,Zachary Grunwald,Yong Huang,Kinya Seo,Philip S Tsao,Daniel Bernstein,Pilar Ruiz-Lozano,Thomas Quertermous,Euan A Ashley

Journal of the American Heart Association 3:e000145 PubMed24772522

2014

Nuclear localization of a1A-adrenergic receptors is required for signaling in cardiac myocytes: an “inside-out” a1-AR signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Steven C Wu,Erika F Dahl,Casey D Wright,Andrew L Cypher,Chastity L Healy,Timothy D O'Connell

Brazilian journal of medical and biological resear 46:128-37 PubMed23369981

2013

TNNI3K is a novel mediator of myofilament function and phosphorylates cardiac troponin I.

Applications

Unspecified application

Species

Unspecified reactive species

Hui Wang,Lin Wang,Li Song,Yan-Wan Zhang,Jue Ye,Rui-Xia Xu,Na Shi,Xian-Min Meng

Circulation research 109:1396-400 PubMed21998327

2011

Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury.

Applications

Species

Pig

Dennis Ladage,Lisa Tilemann,Kiyotake Ishikawa,Robert N Correll,Yoshiaki Kawase,Steven R Houser,Jeffery D Molkentin,Roger J Hajjar

Journal of molecular and cellular cardiology 50:487-99 PubMed21156182

2010

Enhanced myofilament responsiveness upon β-adrenergic stimulation in post-infarct remodeled myocardium.

Applications

Species

Pig

Nicky M Boontje,Daphne Merkus,Ruud Zaremba,Amanda Versteilen,Monique C de Waard,Giulia Mearini,Vincent J de Beer,Lucie Carrier,Lori A Walker,Hans W M Niessen,Dobromir Dobrev,Ger J M Stienen,Dirk J Duncker,Jolanda van der Velden

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Cardiac Troponin I (phospho T143) 抗体

Anti-Cardiac Troponin I (phospho T143) antibody

Western blot - Anti-Cardiac Troponin I (phospho T143) antibody (AB58546)

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

精製に関する特記事項

バッファー組成

出荷温度

短期保存温度

長期保存温度

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (10)

代替製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

組合せ製品

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Abcam product promise