Anti-CALHM1 抗体 (ab106561)
Key features and details
- Rabbit polyclonal to CALHM1
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-CALHM1 antibody -
製品の詳細
Rabbit polyclonal to CALHM1 -
由来種
Rabbit -
特異性
This antibody is predicted to not crossreact with CALHM2 or CALHM3. -
アプリケーション
適用あり: ICC/IF, WB, IHC-Pmore details -
種交差性
交差種: Rat -
免疫原
Synthetic peptide corresponding to 17 amino acids near the amino terminus of Human CALHM1 (NP_001001412).
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ポジティブ･コントロール
- Rat liver tissue lysate; Rat liver tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106561の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF |
Use a concentration of 20 µg/ml.
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| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa.
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| IHC-P |
Use a concentration of 5 µg/ml.
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| 特記事項 |
|---|
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ICC/IF
Use a concentration of 20 µg/ml. |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa. |
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IHC-P
Use a concentration of 5 µg/ml. |
ターゲット情報
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機能
May be a pore-forming ion channel. Controls cytosolic Ca(2+) permeability and cytosolic Ca(2+) concentration. Controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner. -
組織特異性
Predominantly expressed in adult brain. Detected also in retinoic acid-differentiated SH-SY5Y cells. -
配列類似性
Belongs to the FAM26 family. -
細胞内局在
Cell membrane. Endoplasmic reticulum membrane. Colocalizes with HSPA5 at the endoplasmic reticulum. - Information by UniProt
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参照データベース
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別名
- CAHM1_HUMAN antibody
- Calcium homeostasis modulator 1 antibody
- Calcium homeostasis modulator protein 1 antibody
see all
画像
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Western blot - Anti-CALHM1 antibody (ab106561)Lane 1 : Anti-CALHM1 antibody (ab106561) at 1 µg/ml
Lane 2 : Anti-CALHM1 antibody (ab106561) at 2 µg/ml
All lanes : Rat liver tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 38 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CALHM1 antibody (ab106561)Immunohistochemical analysis of CALHM1 in paraffin embedded Rat liver tissue, using ab106561 at 5 µg/ml. -
Immunocytochemistry/ Immunofluorescence - Anti-CALHM1 antibody (ab106561)Immunofluorescence of CALHM1 in Rat Liver cells using ab106561 at 20 ug/ml.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab106561 は 1 報の論文で使用されています。
- Rodriguez M et al. Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells. Front Physiol 12:714785 (2021). PubMed: 34408668