Anti-Calcipressin 1/RCAN1 抗体 (ab185931)
Key features and details
- Rabbit polyclonal to Calcipressin 1/RCAN1
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-Calcipressin 1/RCAN1 antibody
Calcipressin 1/RCAN1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Calcipressin 1/RCAN1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IFmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human Calcipressin 1/RCAN1 aa 50-250.
Database link: P53805 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab185931の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/2000. Predicted molecular weight: 28 kDa.
|
|
| ICC/IF |
Use at an assay dependent concentration.
|
| 特記事項 |
|---|
|
WB
1/500 - 1/2000. Predicted molecular weight: 28 kDa. |
|
ICC/IF
Use at an assay dependent concentration. |
ターゲット情報
-
機能
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. -
組織特異性
Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues. -
配列類似性
Belongs to the RCAN family. - Information by UniProt
-
参照データベース
- Entrez Gene: 1827 Human
- Omim: 602917 Human
- SwissProt: P53805 Human
- Unigene: 282326 Human
-
別名
- Adapt 78 antibody
- Adapt78 antibody
- Calcipressin 1 antibody
see all
画像
-
Immunocytochemistry/ Immunofluorescence - Anti-Calcipressin 1/RCAN1 antibody (ab185931)Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab185931. Blue DAPI for nuclear staining.
-
Western blot - Anti-Calcipressin 1/RCAN1 antibody (ab185931)All lanes : Anti-Calcipressin 1/RCAN1 antibody (ab185931) at 1/500 dilution
Lane 1 : SW480 cell line extract
Lane 2 : SKOV3 cell line extract
Lane 3 : U87 cell line extract
Predicted band size: 28 kDa
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (5)
ab185931 は 5 報の論文で使用されています。
- Xiao JJ et al. Regulator of calcineurin 1 deletion attenuates mitochondrial dysfunction and apoptosis in acute kidney injury through JNK/Mff signaling pathway. Cell Death Dis 13:774 (2022). PubMed: 36071051
- Lao M et al. Regulator of calcineurin 1 gene isoform 4 in pancreatic ductal adenocarcinoma regulates the progression of tumor cells. Oncogene 40:3136-3151 (2021). PubMed: 33824473
- Cheng N et al. Pharmacological Activating Transcription Factor 6 Activation Is Beneficial for Liver Retrieval With ex vivo Normothermic Mechanical Perfusion From Cardiac Dead Donor Rats. Front Surg 8:665260 (2021). PubMed: 34222317
- Song C et al. The competing endogenous circular RNA ADAMTS14 suppressed hepatocellular carcinoma progression through regulating microRNA-572/regulator of calcineurin 1. J Cell Physiol 234:2460-2470 (2019). PubMed: 30317540
- Fang H et al. NF-?B signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via RCAN1 in neonatal rats with hypoxic-ischemic brain damage. Cell Cycle 18:1001-1018 (2019). PubMed: 30990350