Anti-CABP 抗体 [EPR7916] (ab128910)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7916] to CABP
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-CABP antibody [EPR7916]
CABP 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR7916] to CABP -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Human
交差が予測される動物種: Mouse -
免疫原
Synthetic peptide within Human CABP aa 150-250. The exact sequence is proprietary.
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ポジティブ・コントロール
- Y79 and U-87 MG cell lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR7916 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab128910の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/1000 - 1/10000. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
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特記事項 |
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WB
1/1000 - 1/10000. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa). |
ターゲット情報
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機能
Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration. -
組織特異性
Retina and brain. Somatodendritic compartment of neurons. Calbrain was found exclusively in brain where it is abundant in the hippocampus, habenular area in the epithalamus and in the cerebellum. -
配列類似性
Contains 4 EF-hand domains. -
ドメイン
EF-1 binds magnesium constitutively under physiological conditions, EF-3 and EF-4 bind calcium cooperatively and EF-2 binds neither calcium nor magnesium. -
翻訳後修飾
Phosphorylated. The phosphorylation regulates the activity. -
細胞内局在
Cytoplasm > cell cortex. Cell membrane. S-CaBP1 is localized at or near the plasma membrane; Cytoplasm > cytoskeleton. Cytoplasm > perinuclear region. Cell membrane. Golgi apparatus. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. L-CaBP1 is associated most likely with the cytoskeletal structures, whereas S-CaBP1 is localized at or near the plasma membrane and Cytoplasm > cytoskeleton. L-CaBP1 is associated most likely with the cytoskeletal structures. - Information by UniProt
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参照データベース
- Entrez Gene: 9478 Human
- Entrez Gene: 29867 Mouse
- Omim: 605563 Human
- SwissProt: Q9NZU7 Human
- SwissProt: Q9JLK7 Mouse
- Unigene: 458482 Human
- Unigene: 38551 Mouse
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別名
- CABP 1 antibody
- CaBP1 antibody
- CABP1_HUMAN antibody
see all
画像
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All lanes : Anti-CABP antibody [EPR7916] (ab128910) at 1/1000 dilution
Lane 1 : Y79 cell lysate
Lane 2 : U-87 MG cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 40 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab128910 は論文での使用が確認できていません。