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AB181384

Anti-C9orf167 抗体 [EPR13193]

Anti-C9orf167 antibody [EPR13193]

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(1 Publication)

Rabbit Recombinant Monoclonal C9orf167 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 1 publication.

別名を表示する

C9orf167, TOR4A, Torsin-4A, Torsin family 4 member A

2 Images
Immunoprecipitation - Anti-C9orf167 antibody [EPR13193] (AB181384)
  • IP

Supplier Data

Immunoprecipitation - Anti-C9orf167 antibody [EPR13193] (AB181384)

Western blot analysis on immunoprecipitation pellet from HeLa cell lysate (lane 1) labeling C9orf167 with ab181384 at 1/10 dilution or 1X PBS (lane 2) negative control. HRP-conjugated anti-Rabbit IgG preferentially detecting the non-reduced form of Rabbit IgG.

All lanes:

Immunoprecipitation - Anti-C9orf167 antibody [EPR13193] (ab181384)

Predicted band size: 47 kDa

false

Western blot - Anti-C9orf167 antibody [EPR13193] (AB181384)
  • WB

Supplier Data

Western blot - Anti-C9orf167 antibody [EPR13193] (AB181384)

All lanes:

Western blot - Anti-C9orf167 antibody [EPR13193] (ab181384) at 1/1000 dilution

Lane 1:

Human colon cancer tissue lysate at 10 µg

Lane 2:

Human small intestine tissue lysate at 10 µg

Lane 3:

HeLa cell lysate at 10 µg

Lane 4:

HCT-116 cell lysate at 10 µg

Predicted band size: 47 kDa

false

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR13193

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

WB, IP

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/10 - 1/100", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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製品の詳細

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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出荷温度及び保存条件

製品の状態
Liquid
精製度
Tissue culture supernatant
バッファー組成
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

C9orf167 also known as neuron navigator 3 (NAV3) is a protein with a mass of approximately 189 kDa. It is part of the neuron navigator family. This protein exists in various tissues with high expression levels noted in the nervous system. C9orf167 plays a role in cytoskeletal dynamics and cellular processes involving actin and microtubules.
Biological function summary

C9orf167 influences cell morphology and motility by associating with elements that control the cytoskeleton. While it does not typically form part of a stable complex on its own it indirectly interacts with other proteins to mediate changes in cell structure. Its regulatory actions help guide axon pathfinding an essential process for neural network formation.

Pathways

C9orf167 contributes to the regulation of the Wnt signaling pathway and the axonal guidance pathway. This protein interacts with proteins like Dishevelled (related to the Wnt pathway) and also plays roles in the signaling pathways that direct growth cones in neurons ensuring correct neural circuit connections.

C9orf167 connections include roles in neurodevelopmental disorders and cancer. Alterations in its expression or function correlate with conditions such as autism alongside some cancer types like gliomas. In these contexts C9orf167 often interacts with proteins like PTEN which can influence tumor suppressive pathways and neural developmental processes.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

See full target information TOR4A
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Annals of translational medicine 10:767 PubMed35965801

2022

Self-assembled complete hair follicle organoids by coculture of neonatal mouse epidermal cells and dermal cells in Matrigel.

Applications

Unspecified application

Species

Unspecified reactive species

Sitian Xie,Liyun Chen,Mingjun Zhang,Cuiping Zhang,Haihong Li
View all publications
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