Anti-C8 抗体 [056B-373] (ab59140)
Key features and details
- Mouse monoclonal [056B-373] to C8
- Suitable for: ELISA, IHC-Fr, Flow Cyt, WB
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-C8 antibody [056B-373] -
製品の詳細
Mouse monoclonal [056B-373] to C8 -
由来種
Mouse -
アプリケーション
適用あり: ELISA, IHC-Fr, Flow Cyt, WBmore details -
種交差性
交差種: Human -
免疫原
Full length native protein (purified) corresponding to Human C8. Purified human C8
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ポジティブ･コントロール
- Kidney from post streptoccal glomerulonephritis patients.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.1% Sodium azide
Constituent: 99% Borate buffered saline -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
056B-373 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Conjugation kits
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab59140の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ELISA |
Use at an assay dependent concentration.
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| IHC-Fr |
Use at an assay dependent concentration.
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| Flow Cyt |
Use at an assay dependent concentration.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
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| WB |
Use at an assay dependent concentration.
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| 特記事項 |
|---|
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ELISA
Use at an assay dependent concentration. |
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IHC-Fr
Use at an assay dependent concentration. |
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Flow Cyt
Use at an assay dependent concentration. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
WB
Use at an assay dependent concentration. |
ターゲット情報
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関連性
C8 is synthesised in the liver, monocytes and fibroblasts and is a plasma protein consisting of three non identical polypeptide chains. The alpha-chain (64kDa) and gamma chain (22kDa) are disulphide linked, these associate non-covalently with the beta-chain (64kDa), to form the native C8 molecule with a molecular weight of 151kDa. Normal plasma concentration is 80mg/L. C8 is one of the terminal proteins of the complement pathways. C8 binds to the membrane bound C5b-7, C5b-8 combines with C9 to form the membrane attack complex (MAC). The MAC forms a hydrophilic, protein walled, transmembrane channel, formation of which leads to cell lysis and destruction. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 731 Human
- Entrez Gene: 732 Human
- Entrez Gene: 733 Human
- Omim: 120930 Human
- Omim: 120950 Human
- Omim: 120960 Human
- SwissProt: P07357 Human
- SwissProt: P07358 Human
see all -
別名
- C8A antibody
- C8B antibody
- C8G antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab59140 は論文での使用が確認できていません。