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Anti-C5 / C5b 抗体 [568] (ab11879)

Submit a review Q&A (1)References (1)

Key features and details

  • Mouse monoclonal [568] to C5 / C5b
  • Suitable for: WB
  • Reacts with: Human
  • Isotype: IgG2a

製品の概要

  • 製品名

    Anti-C5 / C5b antibody [568]
    C5 / C5b 一次抗体 製品一覧

  • 製品の詳細

    Mouse monoclonal [568] to C5 / C5b

  • 由来種

    Mouse

  • 特異性

    This antibody reacts with an epitope on C5 and on C5b.

  • アプリケーション

    適用あり: WBmore details

  • 種交差性

    交差種: Human

  • 免疫原

    Full length native protein (purified). This information is proprietary to Abcam and/or its suppliers.

  • 特記事項

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab11879の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
WB
Use at an assay dependent concentration.
特記事項
WB
Use at an assay dependent concentration.

ターゲット情報

  • 関連性

    C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190kDa glycoprotein consisting of a disulphide linked alpha-chain (115kDa) and beta-chain (75kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).

  • 細胞内局在

    Secreted

  • 参照データベース

    • 別名

      • C5 antibody
      • Complement C5 antibody
      • Complement component 5 antibody
      • CPAMD4 antibody

    参考文献 (1)

    ab11879 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab11879 は 1 報の論文で使用されています。

    • Liu Z  et al. Super-Resolution Microscopy and FIB-SEM Imaging Reveal Parental Centriole-Derived, Hybrid Cilium in Mammalian Multiciliated Cells. Dev Cell 55:224-236.e6 (2020). PubMed: 33038333

    レビューと Q&A

    Show All レビュー Q&A
    レビューを送る 質問を送る

    Question

    Can you please give me some information about cross-reactivity, especially to human C5a?

    Read More
    Answer

    ab11879 is only able to recognize whole C5 or C5b as the epitope lies in the C5b region. Therefore, there should not be any cross-reactivity with C5a.

    Read More

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