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AB17452

Anti-C2 抗体 [6E3]

Anti-C2 antibody [6E3]

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(1 Publication)

Mouse Monoclonal C2 antibody. Suitable for ELISA, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Native Full Length Protein corresponding to Human C2.

別名を表示する

Complement C2, C3/C5 convertase, C2

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

6E3

アイソタイプ

IgG1

軽鎖のタイプ

kappa

キャリアフリー

No

交差種

Human

アプリケーション

ELISA, WB

applications

免疫原

Native Full Length Protein corresponding to Human C2.

P06681

エピトープ

Epitope specificity differs from that of ab17451 as determined by inhibition ELISA.

特異性

Strong reaction is seen with human serum/plasma and no reaction is seen with serum from patients deficient in C2. ab17452 reacts with C2 and a subfraction of C2 believed to be C2b.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein G
バッファー組成
pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS, 2.9% Sodium chloride
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments : C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
See full target information C2

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

BMC immunology 11:43 PubMed20727163

2010

Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases.

Applications

sELISA

Species

Human

Paolo G V Martini,Lynette C Cook,Scott Alderucci,Angela W Norton,Dianna M Lundberg,Susan M Fish,Knut Langsetmo,Göran Jönsson,Christian Lood,Birgitta Gullstrand,Kate J Zaleski,Nancy Savioli,Jason Lottherand,Charles Bedard,John Gill,Michael F Concino,Michael W Heartlein,Lennart Truedsson,Jan L Powell,Arthur O Tzianabos
View all publications

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