AB155060

Anti-C1r 抗体

Name: Anti-C1r 抗体 (ab155060) | Abcam
Brand: Abcam Limited
SKU: AB155060
Price: 76000 JPY
Availability: InStock

Anti-C1r antibody

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(2 Publications)

Rabbit Polyclonal C1r antibody. Suitable for WB, ICC/IF and reacts with Human, Rat, Mouse samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human C1R aa 250 to C-terminus.

別名を表示する

Complement C1r subcomponent, Complement component 1 subcomponent r, C1R

4 Images

Immunocytochemistry/ Immunofluorescence - Anti-C1r antibody (AB155060)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-C1r antibody (AB155060)

Immunofluorescent analysis of methanol-fixed HCT116 cells labeling C1r with ab155060 at 1/500 dilution. Lower image shows cells co-stained with Hoechst 33342.

Supplier Data

Western blot - Anti-C1r antibody (AB155060)

Samples were separated by 12% SDS-PAGE.

All lanes:

Western blot - Anti-C1r antibody (ab155060) at 1/500 dilution

All lanes:

Human plasma at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 80 kDa

false

Supplier Data

Western blot - Anti-C1r antibody (AB155060)

Samples were separated by 12% SDS-PAGE.

All lanes:

Western blot - Anti-C1r antibody (ab155060) at 1/500 dilution

All lanes:

Mouse plasma at 50 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 80 kDa

false

Supplier Data

Western blot - Anti-C1r antibody (AB155060)

Samples were separated by 12% SDS-PAGE.

All lanes:

Western blot - Anti-C1r antibody (ab155060) at 1/500 dilution

All lanes:

Rat plasma at 50 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 80 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Human, Mouse, Rat

アプリケーション

WB, ICC/IF

applications

免疫原

Recombinant Fragment Protein within Human C1R aa 250 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P00736

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Immunogen

バッファー組成

pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine

出荷温度

Blue Ice

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Serine protease component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system (PubMed : 17996945, PubMed : 19473974, PubMed : 29449492). C1R catalyzes the first enzymatic step in the classical complement pathway : it is activated by the C1Q subcomplex of the C1 complex, which associates with IgG or IgM immunoglobulins complexed with antigens to form antigen-antibody complexes on the surface of pathogens (PubMed : 29449492, PubMed : 34155115). Immunoglobulin-binding promotes the autocatalytic cleavage and activation of C1R (PubMed : 11445589, PubMed : 11673533, PubMed : 17996945, PubMed : 20178990, PubMed : 6254570, PubMed : 6271784). Activated C1R then cleaves and activates C1S, the second protease of the classical complement pathway (PubMed : 11445589, PubMed : 11673533, PubMed : 6271784). It is unclear if C1R activates C1S within single, strained C1 complexes or between neighboring C1 complexes on surfaces (PubMed : 28104818, PubMed : 29311313, PubMed : 29449492).

See full target information C1R

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cell and developmental biology 13:1623135 PubMed40666290

2025

ELK1 regulates BMPR1B transcriptional activity in ovine granulosa cells.

Applications

Unspecified application

Species

Unspecified reactive species

Anwar Abdurahman,Yuling Ga,Xuehai Ma

Cancer immunology research 7:1091-1105 PubMed31164356

2019

Tumor Cells Hijack Macrophage-Produced Complement C1q to Promote Tumor Growth.

Applications

Unspecified application

Species

Unspecified reactive species

Lubka T Roumenina,Marie V Daugan,Rémi Noé,Florent Petitprez,Yann A Vano,Rafaël Sanchez-Salas,Etienne Becht,Julie Meilleroux,Bénédicte Le Clec'h,Nicolas A Giraldo,Nicolas S Merle,Cheng-Ming Sun,Virginie Verkarre,Pierre Validire,Janick Selves,Laetitia Lacroix,Olivier Delfour,Isabelle Vandenberghe,Celine Thuilliez,Sonia Keddani,Imene B Sakhi,Eric Barret,Pierre Ferré,Nathalie Corvaïa,Alexandre Passioukov,Eric Chetaille,Marina Botto,Aurélien de Reynies,Stephane Marie Oudard,Arnaud Mejean,Xavier Cathelineau,Catherine Sautès-Fridman,Wolf H Fridman

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-C1r 抗体

Anti-C1r antibody

Immunocytochemistry/ Immunofluorescence - Anti-C1r antibody (AB155060)

Western blot - Anti-C1r antibody (AB155060)

Western blot - Anti-C1r antibody (AB155060)

Western blot - Anti-C1r antibody (AB155060)

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

代替製品

Primary Antibodies

Primary Antibodies

組合せ製品

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (2)

Abcam product promise