JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB70517

Anti-C17orf57 抗体

Anti-C17orf57 antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Mouse Polyclonal C17orf57 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human EFCAB13.

別名を表示する

C17orf57, EFCAB13, EF-hand calcium-binding domain-containing protein 13

Key facts

宿主種

Mouse

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

Yes

交差種

Human

アプリケーション

WB

applications

免疫原

Recombinant Full Length Protein corresponding to Human EFCAB13.

Q8IY85

style
left-column

組合せ製品

Primary Antibodies

AB172320

Anti-FOXP2 antibody [73A/8]

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FOXP2 antibody [73A/8] (AB172320)

  • 0
  • 0
Assay Kits

AB215539

Human IL-18 ELISA Kit

Recombinant|SimpleStep

ELISA - Human IL-18 ELISA Kit (AB215539)

  • 5
  • 1
Assay Kits

AB269542

Mouse LBP ELISA Kit (LPS Binding Protein)

Recombinant|SimpleStep

ELISA - Mouse LBP ELISA Kit (LPS Binding Protein) (AB269542)

  • 5
  • 1
Assay Kits

AB218184

Human MMP1 Matched Antibody Pair Kit

Recombinant

ELISA - Human MMP1 Matched Antibody Pair Kit (AB218184)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p>Predicted molecular weight for isoform 2:60 kDa</p>" } } }
style
left-column
style
left-column

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein G
バッファー組成
pH: 7.4 Constituents: PBS
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
style
left-column

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

C17orf57 also known as GCP2 or GC-rich promoter binding protein 2 is a 17 kDa protein. It has a role in transcriptional regulation processes. This protein is ubiquitously expressed with higher levels in tissues such as the brain and skeletal muscle. It connects to RNA processing and possibly interacts with various components of the transcription machinery.
Biological function summary

C17orf57 contributes to complex processes involved in the regulation of gene expression. It interacts with some components of RNA polymerase II. This interaction suggests that C17orf57 might assist in modulating the synthesis of RNA transcripts a critical step in the flow of genetic information from DNA to protein. This protein may also play a part in nuclear processes related to mRNA stability and localization.

Pathways

C17orf57 plays a significant role in transcription regulation and RNA processing pathways. It works alongside components in the DNA-dependent transcription pathway where interactions with RNA polymerase II are relevant. Additionally C17orf57's presence in an mRNA processing pathway suggests its involvement with proteins like GRWD1 which are associated with gene expression and regulatory events.

C17orf57 has some association with cancer and neurodegenerative diseases. Studies show that its dysregulation may impact cellular processes leading to abnormal cell proliferation and possibly contributing to oncogenesis. C17orf57's interactions with proteins like CTCF may influence chromatin architecture which can impact regulatory pathways involved in these diseases. Alterations in its expression or function might also influence conditions affecting nervous system health.
style
left-column
style
left-column

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

ターゲットの情報

See full target information EFCAB13
style
left-column

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of molecular medicine (Berlin, Germany) 90:895-910 PubMed22367478

2012

Disruption of mindin exacerbates cardiac hypertrophy and fibrosis.

Applications

Unspecified application

Species

Unspecified reactive species

Zhou-Yan Bian,Xiang Wei,Shan Deng,Qi-Zhu Tang,Jinghua Feng,Yan Zhang,Chen Liu,Ding-Sheng Jiang,Ling Yan,Lian-Feng Zhang,Manyin Chen,John Fassett,Yingjie Chen,You-Wen He,Qinglin Yang,Peter P Liu,Hongliang Li
View all publications
style
left-column
style
left-column
style
right-column

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com