AB181987

Anti-C16orf70 抗体 [EPR14035]

Anti-C16orf70 antibody [EPR14035]

RabMAb
Recombinant
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(2 Publications)

Rabbit Recombinant Monoclonal C16orf70 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 2 publications.

別名を表示する

C16orf6, C16orf70, PHAF1, Phagosome assembly factor 1

2 Images

Supplier Data

Immunoprecipitation - Anti-C16orf70 antibody [EPR14035] (AB181987)

Immunoprecipitation of SH-SY5Y cell lysate, labeling C16orf70 usinf ab181987 at a 1/30 dilution (lane 1) or a negative control (lane 2). Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at a 1/5000 dilution.

All lanes:

Immunoprecipitation - Anti-C16orf70 antibody [EPR14035] (ab181987)

Predicted band size: 48 kDa

false

Supplier Data

Western blot - Anti-C16orf70 antibody [EPR14035] (AB181987)

All lanes:

Western blot - Anti-C16orf70 antibody [EPR14035] (ab181987) at 1/1000 dilution

Lane 1:

Human fetal brain cell lysate at 20 µg

Lane 2:

U87-MG cell lysate at 20 µg

Lane 3:

SH-SY5Y cell lysate at 20 µg

Lane 4:

JAR cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 48 kDa

false

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR14035

アイソタイプ

IgG

キャリアフリー

交差種

Human

アプリケーション

IP, WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/30", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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製品の詳細

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein A

バッファー組成

Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

出荷温度

Conditional Ambient

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

C16orf70 also known as Chromosome 16 Open Reading Frame 70 codes for a protein with a mass approximately of 17 kDa. This protein is mainly expressed in tissues such as the liver and lungs. C16orf70 may involve various functions in cellular processes but it lacks extensive characterization. Researchers aim to understand its role in different cellular contexts as it may hold significance in tissue-specific functions.

Biological function summary

The actions of C16orf70 suggest involvement in cellular signaling pathways. Studies hint at its participation in protein complexes although exact partners require further identification. Its presence in certain tissues implies a potential role linked to intercellular communication possibly influencing cell growth or immune responses. Further research continues to explore these biological interactions.

Pathways

C16orf70 might engage in critical roles within pathways like the Wnt signaling and cellular senescence. Its interactions with other proteins possibly including those from the Wnt pathway suggest involvement in regulating gene expression and maintaining cellular health. Understanding its precise function in these pathways will provide deeper insights into cell regulation and development.

Researchers link C16orf70 to conditions like cancer and chronic obstructive pulmonary disease (COPD). The protein's altered expression or function may interfere with cellular pathways highlighting associations with oncogenic or inflammatory processes. Studies investigate its connection with proteins involved in these disorders aiming to uncover potential therapeutic targets or biomarkers.

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Plays a regulatory role in autophagic activity. In complex with BCAS3, associates with the autophagosome formation site during both non-selective and selective autophagy.

See full target information PHAF1

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Molecular carcinogenesis 64:652-667 PubMed39783768

2025

RNF7-Mediated ROS Targets Malignant Phenotype and Radiotherapy Sensitivity in Glioma With Different IDH1 Genotypes.

Applications

Unspecified application

Species

Unspecified reactive species

Yiran Tao,Zimin Shi,Xianyin Liang,Yuqian Zheng,Lirui Dai,Xiang Li,Zian Li,Wulong Liang,Gaojie Bai,Hao Li,Yuan Lyu,Junqi Li,Tao Zhang,Weihua Hu,Shaolong Zhou,Qiao Shan,Xudong Fu,Xinjun Wang

The Journal of clinical investigation 134: PubMed38869949

2024

C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals.

Applications

Unspecified application

Species

Unspecified reactive species

Anais Franco-Romero,Valeria Morbidoni,Giulia Milan,Roberta Sartori,Jesper Wulff,Vanina Romanello,Andrea Armani,Leonardo Salviati,Maria Conte,Stefano Salvioli,Claudio Franceschi,Viviana Buonomo,Casey O Swoboda,Paolo Grumati,Luca Pannone,Simone Martinelli,Harold Bj Jefferies,Ivan Dikic,Jennifer van der Laan,Filipe Cabreiro,Douglas P Millay,Sharon A Tooze,Eva Trevisson,Marco Sandri

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-C16orf70 抗体 [EPR14035]

Anti-C16orf70 antibody [EPR14035]

Immunoprecipitation - Anti-C16orf70 antibody [EPR14035] (AB181987)

Western blot - Anti-C16orf70 antibody [EPR14035] (AB181987)

関連する標識済み抗体及び組成の異なる製品 (1)

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

組合せ製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

製品の詳細

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (2)

Abcam product promise